Propylene Oxide

Propylene Oxide

SCHEMBL18918976

C1CO1.CC1CO1.CCCCOCCCC

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.55
ALDH1A1 P00352 3/20 0.47
TDP1 Q9NUW8 1/20 0.47
TSHR P16473 3/20 0.43
SPHK2 Q9NRA0 2/20 0.39
SPHK1 Q9NYA1 1/20 0.39
CYP3A4 P08684 1/20 0.38
EPHX1 P07099 1/20 0.38
LMNA P02545 1/20 0.37
POLB P06746 1/20 0.37
GBA2 Q9HCG7 2/20 0.35
GBA1 P04062 1/20 0.35
PDK1 Q15118 1/20 0.35
MEN1 O00255 1/20 0.34
THRB P10828 1/20 0.34
HTT P42858 1/20 0.34
KMT2A Q03164 1/20 0.34
MAPT P10636 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propylene Oxide SCHEMBL1525972 0.93 SMN1; SMN2 (0.61) SMN1; SMN2ALDH1A1TDP1TSHRSPHK2
Propylene Oxide SCHEMBL29394757 0.92 ALDH1A1 (0.58) SMN1; SMN2ALDH1A1TDP1SPHK2SPHK1
Propylene Oxide SCHEMBL28774031 0.89 SMN1; SMN2 (0.57) SMN1; SMN2ALDH1A1TDP1TSHRSPHK2
Propylene Oxide SCHEMBL17709716 0.86 ALDH1A1 (0.61) SMN1; SMN2ALDH1A1TDP1TSHRSPHK2
Oxirane SCHEMBL3734225 0.86 TSHR (0.55) SMN1; SMN2ALDH1A1TDP1TSHRCYP3A4
Propylene Oxide SCHEMBL11617409 0.84 ALDH1A1 (0.64) SMN1; SMN2ALDH1A1TDP1TSHRSPHK2
Propylene Oxide SCHEMBL3021904 0.84 ALDH1A1 (0.64) SMN1; SMN2ALDH1A1TDP1TSHRSPHK2
Propylene Oxide SCHEMBL27494658 0.84 ALDH1A1 (0.64) SMN1; SMN2ALDH1A1TDP1TSHRSPHK2
Propylene Oxide SCHEMBL27603327 0.84 ALDH1A1 (0.64) SMN1; SMN2ALDH1A1TDP1TSHRSPHK2
Propylene Oxide SCHEMBL27499207 0.84 ALDH1A1 (0.64) SMN1; SMN2ALDH1A1TDP1TSHRSPHK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116376005-A Preparation method of rosin-based water-based resin and impregnating compound 重庆国际复合材料股份有限公司 2023-07-04 CN claimed
CN-107723711-B Copper polishing agent 惠州大亚湾金盛科技有限公司 2020-02-18 CN claimed
US-20170158984-A1 METHOD FOR DEGUMMING COMPOSITIONS CONTAINING TRIGLYCERIDE CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) 2017-06-08 US claimed
CN-116376005-A Preparation method of rosin-based water-based resin and impregnating compound 重庆国际复合材料股份有限公司 2023-07-04 CN disclosed
CN-107723711-B Copper polishing agent 惠州大亚湾金盛科技有限公司 2020-02-18 CN disclosed
CN-107723711-B Copper polishing agent 惠州大亚湾金盛科技有限公司 2020-02-18 CN disclosed
CN-110777018-A Engine cleaning agent and preparation method thereof 河南井田油料有限公司 2020-02-11 CN disclosed
US-20170158984-A1 METHOD FOR DEGUMMING COMPOSITIONS CONTAINING TRIGLYCERIDE CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) 2017-06-08 US disclosed
CN-106459830-A Process for degumming a composition containing triglycerides 科莱恩产品 (德国) 公司 2017-02-22 CN disclosed