Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | S100A4 | P26447 | 1/20 | 0.34 |
| ▸ | CDC25B | P30305 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29750384 | 1.00 | GSK3A (0.39) | GSK3AGSK3BPDE3BPDE3AS100A4 | |
| Hydrochloric Acid SCHEMBL28537243 | 0.98 | GSK3A (0.37) | GSK3AGSK3BPDE3BPDE3AS100A4 | |
| Hydrochloric Acid SCHEMBL6025174 | 0.98 | GSK3A (0.37) | GSK3AGSK3BPDE3BPDE3AS100A4 | |
| SCHEMBL1953522 | 0.76 | CYP11B2 (0.39) | CA12CA1CA2CA9BLM | |
| SCHEMBL27747524 | 0.76 | CA12 (0.31) | CA12CA1CA2CA9 | |
| SCHEMBL11349207 | 0.74 | GSK3A (0.37) | GSK3AGSK3B | |
| SCHEMBL13859947 | 0.73 | CA12 (0.33) | CA12CA1CA2CA9TSHR | |
| SCHEMBL27650292 | 0.72 | GSK3A (0.39) | GSK3AGSK3B | |
| SCHEMBL4223695 | 0.71 | PDE3B (0.34) | PDE3BPDE3ACDC25BCA12CA1 | |
| SCHEMBL21386817 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3268372-B9 | KV1.3 INHIBITORS AND THEIR MEDICAL APPLICATION | 4SC AG (DE) | 2021-03-31 | — | — | EP | claimed |
| EP-3268372-B1 | KV1.3 INHIBITORS AND THEIR MEDICAL APPLICATION | 4SC AG (DE) | 2020-07-01 | — | — | EP | claimed |
| CN-105906566-A | Alkaloid compound with antibacterial activity in tobaccos as well as preparation method and use of alkaloid compound | 云南中烟工业有限责任公司 | 2016-08-31 | — | — | CN | claimed |
| EP-2709451-A1 | N-LINKED LACTAM M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | Merck Sharp & Dohme Corp. (US) | 2014-03-26 | — | — | EP | claimed |
| WO-2013050637-A1 | OXOISOAPORPHINE NANOCAPSULES FOR TREATING DEPRESSION | UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) | 2013-04-11 | — | — | WO | claimed |
| WO-2013045730-A1 | USE OF OXOISOAPORPHINES IN COMBATING LEISHMANIASIS | UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) | 2013-04-04 | — | — | WO | claimed |
| WO-2012158475-A1 | N-LINKED LACTAM M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | MERCK SHARP & DOHME CORP. (US) | 2012-11-22 | — | — | WO | claimed |
| EP-1891067-A2 | ANDROGEN RECEPTOR MODULATOR COMPOUNDS AND METHODS | LIGAND PHARMACEUTICALS, INC. (US) | 2008-02-27 | — | — | EP | claimed |
| WO-2007005887-A2 | ANDROGEN RECEPTOR MODULATOR COMPOUNDS, COMPOSITIONS AND USES THEREOF | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2007-01-11 | — | — | WO | claimed |
| WO-2006138347-A2 | ANDROGEN RECEPTOR MODULATOR COMPOUNDS AND METHODS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2006-12-28 | — | — | WO | claimed |
| WO-2001016139-A9 | ANDROGEN RECEPTOR MODULATOR COMPOUNDS AND METHODS | LIGAND PHARM INC (US) | 2002-09-19 | — | — | WO | claimed |
| EP-1212330-A1 | ANDROGEN RECEPTOR MODULATOR COMPOUNDS AND METHODS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2002-06-12 | — | — | EP | claimed |
| WO-2001016139-A1 | ANDROGEN RECEPTOR MODULATOR COMPOUNDS AND METHODS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2001-03-08 | — | — | WO | claimed |
| EP-0154190-A1 | Pyridones | MERCK PATENT GmbH (DE) | 1985-09-11 | — | — | EP | claimed |
| CN-119110800-A | Modulators of interferon gene stimulating factor (STING), compositions and methods | 健道生物医药有限公司 | 2024-12-10 | — | — | CN | disclosed |
| CN-118324761-A | USP inhibitor, preparation method and application thereof | 北京华森英诺生物科技有限公司 | 2024-07-12 | — | — | CN | disclosed |
| EP-3833667-B1 | PRMT5 INHIBITORS | MERCK SHARP & DOHME LLC (US) | 2024-03-13 | — | — | EP | disclosed |
| EP-1021397-A1 | BENZANTHRONE COMPOUNDS AND ANTIVIRAL USES THEREOF | TRIMERIS INC. (US) | 2000-07-26 | — | — | EP | disclosed |
| WO-1998039287-A1 | BENZANTHRONE COMPOUNDS AND ANTIVIRAL USES THEREOF | TRIMERIS, INC. (US) | 1998-09-11 | — | — | WO | disclosed |
| US-4600777-A | Method of preparing 1-alkyl-7-oxodecahydroquinolines, and cis(±) and tran(±)isomers so prepared | ELI LILLY AND COMPANY (US) | 1986-07-15 | — | — | US | disclosed |