SCHEMBL1892258

SCHEMBL1892258

NC(O)=CCc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.52
IDO1 P14902 3/20 0.46
NOS1 P29475 3/20 0.46
NOS2 P35228 2/20 0.46
NOS3 P29474 1/20 0.46
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
ARG2 P78540 1/20 0.45
LOXL2 Q9Y4K0 1/20 0.42
TSHR P16473 1/20 0.42
PRSS1 P07477 1/20 0.39
PRSS2 P07478 1/20 0.39
PRSS3 P35030 1/20 0.39
CALM1 P0DP23 1/20 0.39
PLA2G10 O15496 1/20 0.39
PLA2G2A P14555 1/20 0.39
HTR3A P46098 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1072789 0.85 MAOB (0.52) MAOBIDO1NOS1NOS2NOS3
SCHEMBL7376318 0.81 MAOB (0.48) MAOBIDO1NOS1NOS2NOS3
SCHEMBL14363102 0.81 MAOB (0.48) MAOBIDO1NOS1NOS2NOS3
SCHEMBL23644539 0.79 MAOB (0.46) MAOBIDO1NOS1NOS2NOS3
SCHEMBL516688 0.79 MAOB (0.46) MAOBIDO1NOS1NOS2NOS3
SCHEMBL9192371 0.79 MAOB (0.46) MAOBIDO1NOS1NOS2NOS3
SCHEMBL902765 0.79 MAOB (0.57) MAOBIDO1NOS1NOS2NOS3
SCHEMBL6948797 0.78 MAOB (0.44) MAOBIDO1NOS1NOS2NOS3
SCHEMBL8517077 0.78 MAOB (0.44) MAOBIDO1NOS1NOS2NOS3
SCHEMBL6948801 0.78 MAOB (0.44) MAOBIDO1NOS1NOS2NOS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1986606-B1 PHENYLEPHRINE-CONTAINING LIQUID FORMULATIONS WYETH LLC (US) 2019-04-10 EP claimed
US-20150182478-A1 CHEWABLE TABLET CONTAINING PHENYLEPHRINE WYETH CORP (US) 2015-07-02 US claimed
US-20150150976-A1 PHENYLEPHRINE-CONTAINING LIQUID FORMULATIONS HALEON US HOLDINGS LLC 2015-06-04 US claimed
US-8940796-B2 Phenylephrine liquid formulations WYETH LLC (US) 2015-01-27 US claimed
EP-2351554-A1 Enhanced stability phenylephrine liquid compositions Wyeth LLC (US) 2011-08-03 EP claimed
EP-2316425-A1 Liquid formulations comprising an active agent, glycerine and sorbitol Wyeth LLC (US) 2011-05-04 EP claimed
CN-101505738-A Chewable tablet containing phenylephrine WYETH CORP (US) 2009-08-12 CN claimed
EP-2043619-A2 CHEWABLE TABLET CONTAINING PHENYLEPHRINE Wyeth (US) 2009-04-08 EP claimed
EP-2040672-A2 ENHANCED STABILITY PHENYLEPHRINE LIQUID COMPOSITIONS Wyeth (US) 2009-04-01 EP claimed
EP-1986606-A2 PHENYLEPHRINE-CONTAINING LIQUID FORMULATIONS Wyeth a Corporation of the State of Delaware (US) 2008-11-05 EP claimed
US-20080026055-A1 Chewable tablet containing phenylephrine WYETH (US) 2008-01-31 US claimed
WO-2008013710-A2 CHEWABLE TABLET CONTAINING PHENYLEPHRINE WYETH (US) 2008-01-31 WO claimed
US-20080014274-A1 Enhanced stability phenylephrine liquid compositions WYETH (US) 2008-01-17 US claimed
WO-2008008364-A2 ENHANCED STABILITY PHENYLEPHRINE LIQUID COMPOSITIONS WYETH (US) 2008-01-17 WO claimed
WO-2007098128-A2 PHENYLEPHRINE-CONTAINING LIQUID FORMULATIONS WYETH (US) 2007-08-30 WO claimed
US-20070197661-A1 Phenylephrine liquid formulations WYETH (US) 2007-08-23 US claimed
US-6955824-B1 Inhalation composition containing lactose pellets GLAXO GROUP LIMITED (GB) 2005-10-18 US claimed
US-20200269668-A1 Biologically Efficacious Compositions, Articles of Manufacture And Processes For Producing And/Or Using Same VACHON DAVID JOHN (US) 2020-08-27 US disclosed
US-20050266031-A1 Pharmaceutical suspension composition WYETH LLC 2005-12-01 US disclosed
US-6077822-A COMPRISING WATER-INSOLUBLE SALT OF MONO TO OCTA-SACCHARIDE SUGAR ACID WITH BIOLOGICALLY ACTIVE COMPOUND SELECTED FROM AMINOGLYCOSIDES, TETRACYCLINES, POLYPEPTIDES, GLYCOPEPTIDES AND MACROLIDES FOR CONTROLLED RELEASE OF DRUGS DUMEX-ALPHARMA A/S (DK) 2000-06-20 US disclosed