Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 5/20 | 0.44 |
| ▸ | GBA2 | Q9HCG7 | 6/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.35 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.35 |
| ▸ | UGCG | Q16739 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15372290 | 1.00 | GBA1 (0.44) | GBA1GBA2HCRTR2GAATHRB | |
| SCHEMBL13032050 | 0.86 | GBA1 (0.42) | GBA1GBA2GAATHRB | |
| SCHEMBL11992501 | 0.79 | DPP4 (0.42) | GBA1GBA2GAATHRB | |
| SCHEMBL15186923 | 0.78 | GBA1 (0.42) | GBA1GBA2GAATHRB | |
| SCHEMBL3360203 | 0.78 | GBA1 (0.42) | GBA1GBA2GAATHRB | |
| SCHEMBL3360199 | 0.78 | GBA1 (0.42) | GBA1GBA2GAATHRB | |
| SCHEMBL13942058 | 0.78 | GBA1 (0.42) | GBA1GBA2GAATHRB | |
| SCHEMBL4258808 | 0.77 | CHRNB2 (0.36) | GBA1CHRNB2CHRNA3CHRNA4CHRNB3 | |
| SCHEMBL4248760 | 0.77 | CHRNB2 (0.36) | GBA1CHRNB2CHRNA3CHRNA4CHRNB3 | |
| SCHEMBL4259086 | 0.77 | CHRNB2 (0.36) | GBA1CHRNB2CHRNA3CHRNA4CHRNB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670195-B2 | Glycosidase inhibitors and uses thereof | ALECTOS THERAPEUTICS INC. (CA) | 2017-06-06 | — | — | US | disclosed |