Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SI | P14410 | 2/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 4/20 | 0.30 |
| ▸ | PYGL | P06737 | 1/20 | 0.30 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | GLB1 | P16278 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7049895 | 0.74 | — | — | |
| SCHEMBL21283415 | 0.72 | SI (0.42) | SIMGAMGBA1 | |
| SCHEMBL17691127 | 0.70 | SI (0.52) | SIMGAMGBA1PYGLGBA2 | |
| SCHEMBL15820695 | 0.69 | GLA (0.33) | SIMGAMGBA1GBA2GAA | |
| SCHEMBL10050525 | 0.69 | GLA (0.33) | SIMGAMGBA1GBA2GAA | |
| SCHEMBL9606173 | 0.69 | GLA (0.33) | SIMGAMGBA1GBA2GAA | |
| SCHEMBL15820693 | 0.69 | GLA (0.33) | SIMGAMGBA1GBA2GAA | |
| SCHEMBL10721806 | 0.69 | GLA (0.33) | SIMGAMGBA1GBA2GAA | |
| SCHEMBL23264233 | 0.68 | SI (0.38) | SIMGAM | |
| SCHEMBL466113 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670225-B2 | HIV-1 protease inhibitors and uses thereof | PURDUE RESEARCH FOUNDATION (US) | 2017-06-06 | — | — | US | disclosed |