⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13374875 | 0.91 | CYP2D6 (0.33) | — | |
| SCHEMBL17337592 | 0.91 | CYP2D6 (0.33) | — | |
| SCHEMBL18289855 | 0.91 | CYP2D6 (0.33) | — | |
| SCHEMBL21708027 | 0.91 | CYP2D6 (0.33) | — | |
| SCHEMBL17337593 | 0.91 | CYP2D6 (0.33) | — | |
| SCHEMBL25721685 | 0.91 | CYP2D6 (0.33) | — | |
| SCHEMBL14962705 | 0.91 | CYP2D6 (0.33) | — | |
| SCHEMBL21708028 | 0.91 | CYP2D6 (0.33) | — | |
| SCHEMBL19303632 | 0.82 | DPP4 (0.31) | — | |
| SCHEMBL22472702 | 0.82 | DPP4 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10633448-B2 | IGF-1R antibody-drug-conjugate and its use for the treatment of cancer | PIERRE FABRE MEDICAMENT (FR) | 2020-04-28 | — | — | US | disclosed |
| US-9669106-B2 | Conjugate of monomethyl auristatin F and trastuzumab and its use for the treatment of cancer | PIERRE FABRE MEDICAMENT (FR) | 2017-06-06 | — | — | US | disclosed |