Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21708027 | 1.00 | CYP2D6 (0.33) | CYP2D6DPP4 | |
| SCHEMBL17337592 | 1.00 | CYP2D6 (0.33) | CYP2D6DPP4 | |
| SCHEMBL13374875 | 1.00 | CYP2D6 (0.33) | CYP2D6DPP4 | |
| SCHEMBL17337593 | 1.00 | CYP2D6 (0.33) | CYP2D6DPP4 | |
| SCHEMBL18289855 | 1.00 | CYP2D6 (0.33) | CYP2D6DPP4 | |
| SCHEMBL25721685 | 1.00 | CYP2D6 (0.33) | CYP2D6DPP4 | |
| SCHEMBL14962705 | 1.00 | CYP2D6 (0.33) | CYP2D6DPP4 | |
| SCHEMBL18923780 | 0.91 | — | — | |
| SCHEMBL31032956 | 0.91 | DPP4 (0.38) | CYP2D6DPP4 | |
| SCHEMBL21117488 | 0.90 | CYP2D6 (0.32) | CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3154997-B9 | AURISTATIN DERIVATIVES AND CONJUGATES THEREOF | NOVARTIS AG (CH) | 2021-04-14 | — | — | EP | disclosed |
| EP-3154997-B1 | AURISTATIN DERIVATIVES AND CONJUGATES THEREOF | NOVARTIS AG (CH) | 2020-02-19 | — | — | EP | disclosed |