Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25571882 | 0.92 | F10 (0.43) | F10KMT2AHTTMEN1TAAR1 | |
| SCHEMBL23106249 | 0.91 | ALDH1A1 (0.42) | F10KMT2AHTTALDH1A1GAA | |
| SCHEMBL23809542 | 0.90 | F10 (0.40) | F10KMT2AHTTMEN1TAAR1 | |
| SCHEMBL20821481 | 0.90 | F10 (0.43) | F10KMT2AHTTMEN1TAAR1 | |
| SCHEMBL18923749 | 0.90 | F10 (0.47) | F10KMT2AHTTMEN1TAAR1 | |
| SCHEMBL20621566 | 0.90 | F10 (0.41) | F10KMT2AHTTMEN1TAAR1 | |
| SCHEMBL19119872 | 0.89 | F10 (0.43) | F10KMT2AHTTMEN1TAAR1 | |
| SCHEMBL23809317 | 0.89 | NR1H4 (0.40) | F10KMT2AHTTMEN1TAAR1 | |
| SCHEMBL24002390 | 0.87 | GAA (0.46) | F10KMT2AMEN1TAAR1ALDH1A1 | |
| SCHEMBL21575546 | 0.85 | ALDH1A1 (0.37) | F10KMT2AHTTMEN1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2940029-B1 | DESIGN AND SYNTHESIS OF CLEAVABLE FLUORESCENT NUCLEOTIDES AS REVERSIBLE TERMINATORS FOR DNA SEQUENCING BY SYNTHESIS | UNIV COLUMBIA (US) | 2023-11-29 | — | — | EP | disclosed |
| US-9670539-B2 | Synthesis of cleavable fluorescent nucleotides as reversible terminators for DNA sequencing by synthesis | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2017-06-06 | — | — | US | disclosed |