SCHEMBL18923938

SCHEMBL18923938

COCCOCCNC(=O)CCCNC(=O)CCCCCCCCCCCCC(=O)O

nearest known ligand 0.56

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.56
ALDH1A1 P00352 1/20 0.51
HPGD P15428 2/20 0.50
HTT P42858 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
KDM4E B2RXH2 2/20 0.48
EPHX2 P34913 3/20 0.48
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
ADRA1A P35348 1/20 0.45
GLP1R P43220 8/20 0.44
LMNA P02545 1/20 0.43
PRMT1 Q99873 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18923980 1.00 TSHR (0.56) TSHRALDH1A1HPGDHTTSMN1; SMN2
SCHEMBL12673953 0.97 ALDH1A1 (0.55) TSHRALDH1A1HPGDHTTSMN1; SMN2
SCHEMBL20151931 0.97 ALDH1A1 (0.55) TSHRALDH1A1HPGDHTTSMN1; SMN2
SCHEMBL11921661 0.97 ALDH1A1 (0.55) TSHRALDH1A1HPGDHTTSMN1; SMN2
SCHEMBL12666089 0.92 TSHR (0.62) TSHRALDH1A1HPGDHTTSMN1; SMN2
SCHEMBL12666182 0.92 TSHR (0.62) TSHRALDH1A1HPGDHTTSMN1; SMN2
SCHEMBL31296156 0.92 TSHR (0.61) TSHRALDH1A1HPGDHTTSMN1; SMN2
SCHEMBL30771454 0.92 TSHR (0.61) TSHRALDH1A1HPGDHTTSMN1; SMN2
SCHEMBL15784539 0.92 TSHR (0.61) TSHRALDH1A1HPGDHTTSMN1; SMN2
SCHEMBL28794498 0.92 TSHR (0.61) TSHRALDH1A1HPGDHTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9670261-B2 Functionalized exendin-4 derivatives SANOFI (FR) 2017-06-06 US disclosed