Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.47 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA9 | Q16790 | 4/20 | 0.47 |
| ▸ | APP | P05067 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.34 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.34 |
| ▸ | PREP | P48147 | 2/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16069538 | 0.87 | APP (0.48) | CA12CA1CA9APPKDM4E | |
| SCHEMBL16069604 | 0.82 | APP (0.49) | CA12CA1CA9APPKDM4E | |
| SCHEMBL16069530 | 0.81 | MAPT (0.42) | KDM4EALDH1A1CYP3A4MAPTHPGD | |
| SCHEMBL18924241 | 0.81 | CA12 (0.50) | CA12CA1CA9APPKDM4E | |
| SCHEMBL16069649 | 0.80 | CA12 (0.45) | CA12CA1CA9APPKDM4E | |
| SCHEMBL17523137 | 0.80 | APP (0.48) | CA12CA1CA9APPKDM4E | |
| SCHEMBL16069652 | 0.79 | ALDH1A1 (0.38) | KDM4EALDH1A1HPGD | |
| SCHEMBL18924109 | 0.78 | MAOB (0.49) | CA12CA1CA9APPKDM4E | |
| SCHEMBL16075040 | 0.76 | MAPT (0.47) | KDM4EALDH1A1CYP3A4MAPTHPGD | |
| SCHEMBL16069587 | 0.76 | MAPT (0.46) | KDM4EALDH1A1CYP3A4MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670170-B2 | Resorufin derivatives for treatment of oxidative stress disorders | BIOELECTRON TECHNOLOGY CORPORATION (US) | 2017-06-06 | — | — | US | disclosed |