Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CDK4 | P11802 | 1/20 | 0.30 |
| ▸ | CCND3 | P30281 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19656342 | 0.96 | RECQL (0.39) | RECQLHDAC8GAACDK4CCND3 | |
| SCHEMBL17570887 | 0.87 | RECQL (0.44) | RECQLHDAC8GAA | |
| SCHEMBL17570906 | 0.78 | RECQL (0.43) | RECQLHDAC8GAA | |
| SCHEMBL17570931 | 0.73 | RECQL (0.47) | RECQLHDAC8GAA | |
| SCHEMBL18411732 | 0.72 | HDAC8 (0.34) | HDAC8 | |
| SCHEMBL19656353 | 0.72 | AOC3 (0.32) | — | |
| SCHEMBL1764760 | 0.71 | APP (0.30) | — | |
| SCHEMBL19663592 | 0.71 | — | — | |
| SCHEMBL13008128 | 0.70 | SIRT2 (0.36) | GAA | |
| SCHEMBL17615245 | 0.69 | CTSL (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9669102-B2 | Cytotoxic benzodiazepine derivatives | IMMUNOGEN, INC. (US) | 2017-06-06 | — | — | US | disclosed |