Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 20/20 | 0.98 |
| ▸ | PDE4D | Q08499 | 8/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17313495 | 0.98 | PDE4B (1.00) | PDE4BPDE4D | |
| SCHEMBL18868935 | 0.91 | PDE4B (0.82) | PDE4BPDE4D | |
| SCHEMBL17313509 | 0.88 | PDE4B (0.82) | PDE4BPDE4D | |
| SCHEMBL17313512 | 0.88 | PDE4B (0.82) | PDE4BPDE4D | |
| SCHEMBL15923295 | 0.87 | PDE4B (0.79) | PDE4BPDE4D | |
| SCHEMBL17313502 | 0.87 | PDE4B (0.79) | PDE4BPDE4D | |
| SCHEMBL17313506 | 0.87 | PDE4B (0.79) | PDE4BPDE4D | |
| SCHEMBL15659835 | 0.87 | PDE4B (0.79) | PDE4BPDE4D | |
| SCHEMBL17313517 | 0.85 | PDE4B (0.77) | PDE4BPDE4D | |
| SCHEMBL17313511 | 0.84 | PDE4B (0.74) | PDE4BPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670189-B2 | Substituted condensed pyrimidine compounds | Grünenthal GmbH (DE) | 2017-06-06 | — | — | US | disclosed |