Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | VNN1 | O95497 | 13/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20215042 | 0.89 | HPGD (0.42) | PTGS1KCNH2VNN1HPGDSMN1; SMN2 | |
| Pantethine SCHEMBL1650348 | 0.89 | PTGS1 (0.56) | PTGS1KCNH2VNN1ZDHHC20 | |
| Pantethine SCHEMBL19544641 | 0.89 | PTGS1 (0.56) | PTGS1KCNH2VNN1ZDHHC20 | |
| Pantethine SCHEMBL59597 | 0.89 | PTGS1 (0.56) | PTGS1KCNH2VNN1ZDHHC20 | |
| Pantethine SCHEMBL8416070 | 0.87 | PTGS1 (0.55) | PTGS1KCNH2VNN1ZDHHC20 | |
| Pantethine SCHEMBL19359043 | 0.87 | PTGS1 (0.55) | PTGS1KCNH2VNN1ZDHHC20 | |
| SCHEMBL22056559 | 0.87 | PTGS1 (0.55) | PTGS1KCNH2VNN1HPGDSMN1; SMN2 | |
| Pantethine SCHEMBL19358994 | 0.87 | PTGS1 (0.55) | PTGS1KCNH2VNN1ZDHHC20 | |
| SCHEMBL12642918 | 0.87 | PTGS1 (0.55) | PTGS1KCNH2VNN1HPGDSMN1; SMN2 | |
| SCHEMBL20033285 | 0.87 | HPGD (0.42) | PTGS1KCNH2VNN1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670153-B2 | Compositions and methods for the treatment of inflammation and lipid disorders | CELLIX BIO PRIVATE LIMITED (IN) | 2017-06-06 | — | — | US | disclosed |