Pantethine

Pantethine

SCHEMBL1650348

CC(C)(CO)[C@@H](O)C(=O)NCCC(=O)NCCSSCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)CO

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.56
KCNH2 Q12809 1/20 0.56
VNN1 O95497 13/20 0.50
ZDHHC20 Q5W0Z9 1/20 0.38
ALDH1A1 P00352 1/20 0.34
HDAC2 Q92769 1/20 0.32
CHAT P28329 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pantethine SCHEMBL19544641 1.00 PTGS1 (0.56) PTGS1KCNH2VNN1ZDHHC20ALDH1A1
Pantethine SCHEMBL59597 1.00 PTGS1 (0.56) PTGS1KCNH2VNN1ZDHHC20ALDH1A1
Pantethine SCHEMBL19358994 0.99 PTGS1 (0.55) PTGS1KCNH2VNN1ZDHHC20ALDH1A1
Pantethine SCHEMBL19359043 0.99 PTGS1 (0.55) PTGS1KCNH2VNN1ZDHHC20ALDH1A1
Pantethine SCHEMBL8416070 0.99 PTGS1 (0.55) PTGS1KCNH2VNN1ZDHHC20ALDH1A1
Pantethine SCHEMBL9112817 0.97 PTGS1 (0.54) PTGS1KCNH2VNN1ZDHHC20ALDH1A1
Pantethine SCHEMBL9115760 0.97 PTGS1 (0.54) PTGS1KCNH2VNN1ZDHHC20ALDH1A1
Pantethine SCHEMBL8416043 0.96 PTGS1 (0.52) PTGS1KCNH2VNN1ZDHHC20ALDH1A1
SCHEMBL18314794 0.95 PTGS1 (0.51) PTGS1KCNH2VNN1ZDHHC20ALDH1A1
SCHEMBL22369798 0.95 PTGS1 (0.51) PTGS1KCNH2VNN1ZDHHC20ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250375406-A1 TREATMENT OF NON-ALCOHOLIC STEATOHEPATITIS AND NON-ALCOHOLIC FATTY LIVER DISEASE VEROSCIENCE LLC (US) 2025-12-11 US claimed
US-20250269022-A1 ASSESSING AND TREATING CANCER MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH 2025-08-28 US claimed
EP-4334718-A1 ASSESSING AND TREATING CANCER Mayo Foundation for Medical Education and Research (US) 2024-03-13 EP claimed
EP-3549574-B1 COMPOSITION FOR PROMOTING HAIR GROWTH OR HAIR RESTORATION, CONTAINING NOVEL PANTETHEINE-BASED SUBSTANCE KOREA INST OCEAN SCI & TECH (KR) 2024-02-14 EP claimed
EP-3628640-B1 METHODS OF MAKING A DEUTERATED OR A NON-DEUTERATED MOLECULE AND PHARMACEUTICAL FORMULATIONS FOR TREATMENT HUB THERAPEUTICS (US) 2023-08-09 EP claimed
CN-116247104-A Thin magnetic semiconductor film material epitaxial structure and preparation method 成都海威华芯科技有限公司 2023-06-09 CN claimed
CN-115650207-B Porous carbon material and preparation method and application thereof 河北省科学院能源研究所 2023-03-21 CN claimed
CN-115650207-A Porous carbon material and preparation method and application thereof 河北省科学院能源研究所 2023-01-31 CN claimed
WO-2022236099-A1 ASSESSING AND TREATING CANCER MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2022-11-10 WO claimed
EP-3197436-B1 COMPOSITIONS AND METHODS FOR SELECTIVE GI TRACT DELIVERY VITAL BEVERAGES GLOBAL INC (VG) 2022-03-09 EP claimed
CN-100402640-C Process for producing lactonase and use thereof DAIICHI FINE CHEM CO LTD (JP) 2008-07-16 CN claimed
CN-1761742-A Process for producing lactonase and use thereof DAIICHI FINE CHEM CO LTD (JP) 2006-04-19 CN claimed
CN-1121497-C D-pantolactone hydrolase and gene encoding the same DAIICHI FINE CHEM CO LTD (JP) 2003-09-17 CN claimed
CN-116247104-B Thin magnetic semiconductor film material epitaxial structure and preparation method CHENGDU HIWAFER TECHNOLOGY Co.,Ltd. (CN) 2026-05-29 CN disclosed
US-20260102359-A1 COMBINATION TREATMENT OF DERMAL AND TRANSDERMAL FIBROTIC DISEASES, DISORDERS AND ASSOCIATED PAIN AND INFLAMMATION ERESINA LLC (US) 2026-04-16 US disclosed
US-12569456-B2 Methods for the treatment of cysteamine sensitive disorders THIOGENESIS THERAPEUTICS, INC. (US) 2026-03-10 US disclosed
CN-1635996-A Topical skin preparation containing 4-hydroxyphenyl-alpha-D-glucopyranoside PENTAPHARM LTD (CH) 2005-07-06 CN disclosed
CN-1121497-C D-pantolactone hydrolase and gene encoding the same DAIICHI FINE CHEM CO LTD (JP) 2003-09-17 CN disclosed
CN-1166182-A D-pantolactone hydrolase and gene encoding the same FUJI YAKUHIN K K K (JP) 1997-11-26 CN disclosed
CN-1101846-A Chinese medicine of anticoagulating and lowering blood fat for cardiovascular and cerebrovascular diseases WANG YINKUN (CN) 1995-04-26 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12569456-B2 Methods for the treatment of cysteamine sensitive disorders SLC7A11, CTH, SLC19A1 PTGS1 365/4885KCNH2 2528/4885VNN1 53/4885
US-20260102359-A1 COMBINATION TREATMENT OF DERMAL AND TRANSDERMAL FIBROTIC DISEASES, DISORDERS AND ASSOCIATED PAIN AND INFLAMMATION COL2A1, COLGALT1, PLOD3 PTGS1 263/4885KCNH2 1639/4885VNN1 1015/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.