Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | ELOVL1 | Q9BW60 | 4/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL803499 | 0.98 | HRH4 (0.48) | HRH4OPRM1OPRL1HCRTR1HCRTR2 | |
| SCHEMBL18924366 | 0.86 | HRH4 (0.52) | HRH4OPRM1OPRL1HRH3ALDH1A1 | |
| SCHEMBL13028832 | 0.85 | PIK3CA (0.50) | OPRM1OPRL1HCRTR1HCRTR2SMN1; SMN2 | |
| SCHEMBL18888320 | 0.82 | HRH4 (0.54) | HRH4OPRM1OPRL1HCRTR1HCRTR2 | |
| SCHEMBL13990855 | 0.82 | HRH4 (0.54) | HRH4OPRM1OPRL1HCRTR1HCRTR2 | |
| SCHEMBL15621623 | 0.81 | HRH4 (0.49) | HRH4OPRM1OPRL1HCRTR1HCRTR2 | |
| SCHEMBL10274925 | 0.80 | HRH4 (0.51) | HRH4OPRM1OPRL1HCRTR1HCRTR2 | |
| SCHEMBL3752158 | 0.79 | HRH4 (0.50) | HRH4OPRM1OPRL1HCRTR1HCRTR2 | |
| SCHEMBL21492519 | 0.79 | LOXL2 (0.51) | HRH4OPRM1OPRL1HCRTR1HCRTR2 | |
| SCHEMBL15504891 | 0.79 | HRH4 (0.50) | HRH4OPRM1OPRL1HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670172-B2 | Heterocyclic compounds and methods of use | MEDIVATION TECHNOLOGIES, INC. (US) | 2017-06-06 | — | — | US | disclosed |