⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24299784 | 0.83 | — | — | |
| SCHEMBL21134401 | 0.82 | — | — | |
| SCHEMBL19369022 | 0.81 | TSHR (0.31) | — | |
| SCHEMBL25163446 | 0.81 | — | — | |
| SCHEMBL15583630 | 0.81 | — | — | |
| SCHEMBL24070106 | 0.74 | — | — | |
| SCHEMBL21134377 | 0.72 | — | — | |
| SCHEMBL24872933 | 0.70 | TSHR (0.30) | — | |
| SCHEMBL21745868 | 0.70 | TSHR (0.30) | — | |
| SCHEMBL28821641 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023282104-A1 | COMPOUND, RAW MATERIAL FOR THIN FILM FORMATION, THIN FILM, AND METHOD FOR PRODUCING THIN FILM | 株式会社ADEKA | 2023-01-12 | — | — | WO | disclosed |
| US-10344031-B2 | Substituted pyrazolo[1,5-a] pyridine as tropomyosin receptor kinase (Trk) inhibitors | DR. REDDY'S LABORATORIES LTD. (IN) | 2019-07-09 | — | — | US | disclosed |
| US-9670207-B2 | Substituted pyrazolo[1,5-a] pyridine as tropomyosin receptor kinase (Trk) inhibitors | DR. REDDY'S LABORATORIES LTD. (IN) | 2017-06-06 | — | — | US | disclosed |