⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21134377 | 0.85 | — | — | |
| SCHEMBL18924336 | 0.82 | — | — | |
| SCHEMBL19369022 | 0.81 | TSHR (0.31) | — | |
| SCHEMBL28821642 | 0.79 | — | — | |
| SCHEMBL24070106 | 0.74 | — | — | |
| SCHEMBL24299784 | 0.74 | — | — | |
| SCHEMBL17173285 | 0.70 | TSHR (0.30) | — | |
| SCHEMBL17173291 | 0.70 | TSHR (0.30) | — | |
| SCHEMBL17832224 | 0.67 | — | — | |
| SCHEMBL25163446 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10344031-B2 | Substituted pyrazolo[1,5-a] pyridine as tropomyosin receptor kinase (Trk) inhibitors | DR. REDDY'S LABORATORIES LTD. (IN) | 2019-07-09 | — | — | US | disclosed |