SCHEMBL18924345

SCHEMBL18924345

CCC(=O)N[C@H]1CC[C@@H](N(C)C(=O)c2ccc(-c3ccc(O)c(F)c3)cc2)C1

nearest known ligand 0.76

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FASN P49327 20/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16323182 0.91 FASN (0.77) FASN
SCHEMBL16365760 0.91 FASN (0.77) FASN
SCHEMBL16324318 0.89 FASN (0.75) FASN
SCHEMBL16365602 0.87 FASN (0.77) FASN
SCHEMBL18924524 0.87 FASN (0.77) FASN
SCHEMBL16324050 0.87 FASN (0.77) FASN
SCHEMBL16322751 0.87 FASN (0.73) FASN
SCHEMBL16365811 0.87 FASN (0.73) FASN
SCHEMBL19391063 0.87 FASN (0.71) FASN
SCHEMBL19391337 0.87 FASN (0.74) FASN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9670142-B2 1,3-diaminocyclopentane carboxamide derivatives MERCK PATENT GMBH (DE) 2017-06-06 US disclosed