Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.43 |
| ▸ | HTR2C | P28335 | 3/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | GHSR | Q92847 | 1/20 | 0.40 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | WNT1 | P04628 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19391081 | 0.89 | ABL1 (0.45) | FASNPOLBABL1KCNH2ROCK2 | |
| SCHEMBL22259511 | 0.84 | AR (0.46) | FASNABL1KCNH2ARGHSR | |
| SCHEMBL10762514 | 0.84 | RAB9A (0.52) | POLBNPC1RAB9A | |
| SCHEMBL19391173 | 0.84 | FASN (0.48) | FASNPOLBKCNH2HTR2CMCHR1 | |
| SCHEMBL19391086 | 0.84 | ABL1 (0.48) | FASNPOLBABL1KCNH2MTOR | |
| SCHEMBL20897035 | 0.83 | RAB9A (0.54) | POLBNPC1RAB9AHPGD | |
| SCHEMBL18924349 | 0.83 | ABL1 (0.47) | FASNABL1KCNH2HTR2CMCHR1 | |
| SCHEMBL18924538 | 0.82 | FASN (0.50) | FASNPOLBABL1KCNH2NPC1 | |
| SCHEMBL16323855 | 0.82 | FASN (0.77) | FASN | |
| SCHEMBL19391174 | 0.81 | POLB (0.44) | FASNPOLBKCNH2HTR2CMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670142-B2 | 1,3-diaminocyclopentane carboxamide derivatives | MERCK PATENT GMBH (DE) | 2017-06-06 | — | — | US | disclosed |