Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.43 |
| ▸ | RXRA | P19793 | 2/20 | 0.43 |
| ▸ | RXRB | P28702 | 2/20 | 0.43 |
| ▸ | RXRG | P48443 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20756090 | 0.82 | RXRA (0.54) | L3MBTL1MRGPRX4RXRARXRBRXRG | |
| SCHEMBL629336 | 0.80 | HTR2A (0.55) | L3MBTL1HTR2CSLC6A4MAPTMAPK1 | |
| SCHEMBL18893896 | 0.76 | MRGPRX4 (0.49) | L3MBTL1MRGPRX4RXRARXRBRXRG | |
| SCHEMBL29937257 | 0.76 | MRGPRX4 (0.49) | L3MBTL1MRGPRX4RXRARXRBRXRG | |
| SCHEMBL16097308 | 0.75 | PDE4B (0.42) | MRGPRX4RXRARXRBRXRG | |
| SCHEMBL20482557 | 0.74 | MRGPRX4 (0.38) | L3MBTL1MRGPRX4RXRARXRBRXRG | |
| SCHEMBL16548414 | 0.74 | MRGPRX4 (0.53) | L3MBTL1MRGPRX4RXRARXRBRXRG | |
| SCHEMBL14453588 | 0.74 | MRGPRX4 (0.50) | L3MBTL1MRGPRX4RXRARXRBRXRG | |
| SCHEMBL16455676 | 0.72 | MAPT (0.47) | L3MBTL1MRGPRX4RXRARXRBRXRG | |
| SCHEMBL6628330 | 0.72 | RXRA (0.71) | L3MBTL1MRGPRX4RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670172-B2 | Heterocyclic compounds and methods of use | MEDIVATION TECHNOLOGIES, INC. (US) | 2017-06-06 | — | — | US | disclosed |