Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 2/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19165885 | 0.84 | PLA2G2A (0.37) | NPC1MAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL19166007 | 0.84 | PLA2G2A (0.37) | NPC1MAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL19165838 | 0.83 | MEN1 (0.38) | NPC1MAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL19165331 | 0.83 | MEN1 (0.38) | NPC1MAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL17486247 | 0.83 | NPC1 (0.53) | NPC1MAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL21742760 | 0.82 | GRM5 (0.39) | NPC1MAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL18924677 | 0.81 | MAPT (0.49) | NPC1MAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL17426588 | 0.80 | CYP2D6 (0.42) | MAPTGRM5CYP2D6 | |
| SCHEMBL22376152 | 0.80 | PLA2G2A (0.46) | NPC1MAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL17756860 | 0.80 | NPC1 (0.47) | NPC1MAPTSMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670241-B2 | Organometallic compound and organic light-emitting device including the same | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2017-06-06 | — | — | US | disclosed |