Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CASR | P41180 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | STAT1 | P42224 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21013849 | 1.00 | LOXL2 (0.61) | LOXL2HPGDCASRALOX5RAB9A | |
| SCHEMBL22919771 | 0.94 | LOXL2 (0.65) | LOXL2HPGDCASRALOX5RAB9A | |
| SCHEMBL20178515 | 0.88 | LOXL2 (0.69) | LOXL2HPGDCASRALOX5RAB9A | |
| SCHEMBL27940631 | 0.85 | LOXL2 (0.50) | LOXL2HPGDCASRALOX5RAB9A | |
| SCHEMBL3469768 | 0.85 | LOXL2 (0.57) | LOXL2HPGDCASRALOX5RAB9A | |
| SCHEMBL27921995 | 0.84 | LOXL2 (0.49) | LOXL2HPGDCASRALOX5RAB9A | |
| SCHEMBL28392684 | 0.84 | LOXL2 (0.72) | LOXL2HPGDCASRALOX5RAB9A | |
| SCHEMBL19370495 | 0.83 | NPC1 (0.41) | LOXL2RAB9ANPC1GAAMAPK1 | |
| Bromide SCHEMBL10646476 | 0.83 | LOXL2 (0.48) | LOXL2HPGDCASRALOX5RAB9A | |
| SCHEMBL21291322 | 0.82 | LOXL2 (0.50) | LOXL2HPGDCASRALOX5RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670157-B2 | Benzylamine derivatives | KALVISTA PHARMACEUTICALS LIMITED (GB) | 2017-06-06 | — | — | US | disclosed |