Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 15/20 | 0.61 |
| ▸ | FER | P16591 | 5/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14929526 | 0.92 | SYK (0.73) | SYKFER | |
| SCHEMBL14910526 | 0.92 | SYK (0.73) | SYKFER | |
| SCHEMBL5026227 | 0.92 | SYK (0.73) | SYKFER | |
| SCHEMBL20750802 | 0.89 | SYK (0.53) | SYKFER | |
| SCHEMBL2715998 | 0.87 | SYK (0.57) | SYKFER | |
| SCHEMBL18926151 | 0.87 | SYK (0.57) | SYKFER | |
| SCHEMBL18925495 | 0.85 | SYK (0.63) | SYKFER | |
| SCHEMBL20750869 | 0.84 | FER (0.48) | SYKFER | |
| SCHEMBL20750870 | 0.82 | SYK (0.61) | SYK | |
| SCHEMBL18925375 | 0.82 | SYK (0.61) | SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3176154-B1 | BENZAMIDES AND NICOTINAMIDES AS SYK MODULATORS | PORTOLA PHARM INC (US) | 2019-02-20 | — | — | EP | disclosed |
| EP-3176154-A1 | BENZAMIDES AND NICOTINAMIDES AS SYK MODULATORS | Portola Pharmaceuticals, Inc. (US) | 2017-06-07 | — | — | EP | disclosed |