Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 14/20 | 0.53 |
| ▸ | FER | P16591 | 6/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18926151 | 0.91 | SYK (0.57) | SYKFER | |
| SCHEMBL2715998 | 0.91 | SYK (0.57) | SYKFER | |
| SCHEMBL18926101 | 0.89 | SYK (0.61) | SYKFER | |
| SCHEMBL20750878 | 0.85 | SYK (0.50) | SYKFER | |
| SCHEMBL18925839 | 0.85 | SYK (0.53) | SYK | |
| SCHEMBL14910526 | 0.84 | SYK (0.73) | SYKFER | |
| SCHEMBL14929526 | 0.84 | SYK (0.73) | SYKFER | |
| SCHEMBL5026227 | 0.84 | SYK (0.73) | SYKFER | |
| SCHEMBL20750747 | 0.84 | SYK (0.61) | SYKFER | |
| SCHEMBL18925379 | 0.84 | SYK (0.61) | SYKFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3176154-B1 | BENZAMIDES AND NICOTINAMIDES AS SYK MODULATORS | PORTOLA PHARM INC (US) | 2019-02-20 | — | — | EP | disclosed |