Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 10/20 | 0.83 |
| ▸ | MAPT | P10636 | 3/20 | 0.83 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.83 |
| ▸ | LMNA | P02545 | 2/20 | 0.83 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.83 |
| ▸ | PGR | P06401 | 2/20 | 0.83 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.83 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.83 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.83 |
| ▸ | AR | P10275 | 2/20 | 0.83 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.83 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.83 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.83 |
| ▸ | DRD1 | P21728 | 2/20 | 0.83 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.83 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.83 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.83 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.83 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.83 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hexestrol SCHEMBL154886 | 0.91 | ESR1 (1.00) | ESR1MAPTALOX15LMNACYP1A2 | |
| Hexestrol SCHEMBL154885 | 0.91 | ESR1 (1.00) | ESR1MAPTALOX15LMNACYP1A2 | |
| SCHEMBL25079595 | 0.85 | ESR1 (0.60) | ESR1MAPTALOX15LMNACYP1A2 | |
| Hexestrol SCHEMBL17628536 | 0.83 | ESR1 (0.83) | ESR1MAPTALOX15LMNACYP1A2 | |
| SCHEMBL12049665 | 0.83 | ACHE (0.56) | ESR1MAPTALOX15LMNACYP1A2 | |
| SCHEMBL17736720 | 0.81 | ESR1 (0.79) | ESR1MAPTALOX15LMNACYP1A2 | |
| Hexestrol SCHEMBL27496510 | 0.81 | ESR1 (0.79) | ESR1MAPTALOX15LMNACYP1A2 | |
| Hexestrol SCHEMBL27352072 | 0.81 | ESR1 (0.79) | ESR1MAPTALOX15LMNACYP1A2 | |
| SCHEMBL4634694 | 0.80 | ESR1 (0.78) | ESR1MAPTALOX15LMNACYP1A2 | |
| SCHEMBL1323678 | 0.80 | ESR1 (0.78) | ESR1MAPTALOX15LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170157064-A1 | METHODS FOR THE TREATMENT OF HEPATITIS C | CIPLA LIMITED (IN) | 2017-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170157064-A1 | METHODS FOR THE TREATMENT OF HEPATITIS C | HAVCR2, HSD17B11, NR1H4 | ESR1 147/4885MAPT 4814/4885ALOX15 1677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.