Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 6/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | CA4 | P22748 | 3/20 | 0.34 |
| ▸ | CA7 | P43166 | 3/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1655758 | 0.82 | PTAFR (0.41) | PTAFR | |
| SCHEMBL30137694 | 0.82 | PTAFR (0.41) | PTAFR | |
| SCHEMBL4539391 | 0.81 | PTAFR (0.35) | PTAFRCA1CA2CA4CA7 | |
| SCHEMBL4532060 | 0.81 | PTAFR (0.35) | PTAFRCA1CA2CA4CA7 | |
| SCHEMBL4529772 | 0.81 | PTAFR (0.35) | PTAFRCA1CA2CA4CA7 | |
| SCHEMBL12362314 | 0.78 | HDAC8 (0.39) | PTAFRCA1CA2CA4CA7 | |
| SCHEMBL4565013 | 0.77 | KDM4E (0.43) | — | |
| SCHEMBL4565014 | 0.77 | KDM4E (0.43) | — | |
| SCHEMBL4565403 | 0.77 | KDM4E (0.41) | — | |
| SCHEMBL4565402 | 0.77 | KDM4E (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2638044-B1 | ALKOXY-SUBSTITUTED 2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLINES | BAYER IP GMBH (DE) | 2017-08-30 | — | — | EP | disclosed |
| EP-2638043-B1 | ARYLAMINOALCOHOL-SUBSTITUTED 2,3-DIHYDROIMIDAZO[1,2-C]QUINOLINES | BAYER IP GMBH (DE) | 2017-06-07 | — | — | EP | disclosed |