⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5203482 | 0.93 | CYP19A1 (0.42) | — | |
| SCHEMBL725806 | 0.91 | CYP19A1 (0.41) | — | |
| SCHEMBL6339919 | 0.86 | — | — | |
| SCHEMBL11361006 | 0.80 | CYP19A1 (0.48) | — | |
| SCHEMBL13017019 | 0.78 | CYP19A1 (0.41) | — | |
| SCHEMBL1289862 | 0.77 | — | — | |
| SCHEMBL724736 | 0.77 | — | — | |
| SCHEMBL1098635 | 0.77 | — | — | |
| SCHEMBL1179086 | 0.77 | — | — | |
| SCHEMBL6221735 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3026049-B1 | METHOD FOR PREPARING BENZAMIDE DERIVATIVE, NOVEL INTERMEDIATE USED IN PREPARATION OF BENZAMIDE, AND METHOD FOR PREPARING NOVEL INTERMEDIATE | DONG A ST CO LTD (KR) | 2021-09-22 | — | — | EP | disclosed |
| CN-105636946-B | Prepare the method for heterocyclic carbamate derivatives, the new intermediate for preparing benzamide and the method for preparing new intermediate | 东亚ST 株式会社 | 2017-12-19 | — | — | CN | disclosed |
| US-9771348-B2 | Method for preparing benzamide derivative, novel intermediate used in preparation of benzamide, and method for preparing novel intermediate | DONG-A ST CO., LTD (KR) | 2017-09-26 | — | — | US | disclosed |
| US-9771348-B2 | Method for preparing benzamide derivative, novel intermediate used in preparation of benzamide, and method for preparing novel intermediate | DONG-A ST CO., LTD (KR) | 2017-09-26 | — | — | US | disclosed |
| US-9771348-B2 | Method for preparing benzamide derivative, novel intermediate used in preparation of benzamide, and method for preparing novel intermediate | DONG-A ST CO., LTD (KR) | 2017-09-26 | — | — | US | disclosed |
| US-20160185751-A1 | METHOD FOR PREPARING BENZAMIDE DERIVATIVE, NOVEL INTERMEDIATE USED IN PREPARATION OF BENZAMIDE, AND METHOD FOR PREPARING NOVEL INTERMEDIATE | DONG-A ST CO., LTD (KR) | 2016-06-30 | — | — | US | disclosed |
| US-20160185751-A1 | METHOD FOR PREPARING BENZAMIDE DERIVATIVE, NOVEL INTERMEDIATE USED IN PREPARATION OF BENZAMIDE, AND METHOD FOR PREPARING NOVEL INTERMEDIATE | DONG-A ST CO., LTD (KR) | 2016-06-30 | — | — | US | disclosed |
| US-20160185751-A1 | METHOD FOR PREPARING BENZAMIDE DERIVATIVE, NOVEL INTERMEDIATE USED IN PREPARATION OF BENZAMIDE, AND METHOD FOR PREPARING NOVEL INTERMEDIATE | DONG-A ST CO., LTD (KR) | 2016-06-30 | — | — | US | disclosed |
| EP-3026049-A1 | METHOD FOR PREPARING BENZAMIDE DERIVATIVE, NOVEL INTERMEDIATE USED IN PREPARATION OF BENZAMIDE, AND METHOD FOR PREPARING NOVEL INTERMEDIATE | Dong-A ST Co., Ltd. (KR) | 2016-06-01 | — | — | EP | disclosed |
| CN-105636946-A | Method for preparing benzamide derivative, novel intermediate used in preparation of benzamide, and method for preparing novel intermediate | DONG A ST CO LTD | 2016-06-01 | — | — | CN | disclosed |
| US-7253286-B2 | Urea derivatives containing aromatic or heteroaromatic rings, useful as prophylactic or therapeutic agent for a disease for which angiogenesis inhibition is effective | EISAI CO., LTD (JP) | 2007-08-07 | — | — | US | disclosed |
| EP-1777218-A1 | Process for the preparation of 4-phenoxy quinoline derivatives | Eisai R&D Management Co., Ltd. (JP) | 2007-04-25 | — | — | EP | disclosed |
| CN-1308310-C | Nitrogen-containing aromatic ring derivatives | EISAI CO LTD (JP) | 2007-04-04 | — | — | CN | disclosed |
| EP-1415987-B1 | NITROGENOUS AROMATIC RING COMPOUNDS AS ANTI CANCER AGENTS | EISAI R&D MAN CO LTD (JP) | 2007-02-28 | — | — | EP | disclosed |
| US-20060247259-A1 | Urea derivatives containing aromatic or heteroaromatic rings; 4-(3-chloro-4-(cyclopropylaminocarbonyl)aminophenoxy)-7-methoxy-6-quinolinecarboxamide; prophylactic or therapeutic agent for a disease for which angiogenesis inhibition is effective | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2006-11-02 | — | — | US | disclosed |
| US-20060160832-A1 | Urea derivatives containing aromatic or heteroaromatic rings; 4-(3-chloro-4-(cyclopropylaminocarbonyl)aminophenoxy)-7-methoxy-6-quinolinecarboxamide; prophylactic or therapeutic agent for a disease for which angiogenesis inhibition is effective | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2006-07-20 | — | — | US | disclosed |
| EP-1506962-A2 | Nitrogen-containing aromatic heterocycles | Eisai Co. Ltd. (JP) | 2005-02-16 | — | — | EP | disclosed |
| EP-1415987-A1 | NITROGENOUS AROMATIC RING COMPOUNDS | Eisai Co., Ltd. (JP) | 2004-05-06 | — | — | EP | disclosed |
| US-20040053908-A1 | Urea derivatives containing aromatic or heteroaromatic rings, useful as prophylactic or therapeutic agent for a disease for which angiogenesis inhibition is effective | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2004-03-18 | — | — | US | disclosed |
| CN-1478078-A | Nitrogen-containing aromatic ring derivatives | ������������ʽ���� | 2004-02-25 | — | — | CN | disclosed |