Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.82 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | ATM | Q13315 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | GPR3 | P46089 | 1/20 | 0.53 |
| ▸ | F2RL3 | Q96RI0 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | F2R | P25116 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | KIF11 | P52732 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7708920 | 0.91 | MAPT (0.67) | MAPTMEN1KMT2ALMNAATM | |
| SCHEMBL150552 | 0.90 | MAPT (1.00) | MAPTMEN1KMT2ALMNAATM | |
| SCHEMBL22282320 | 0.83 | MAPT (0.80) | MAPTMEN1KMT2ALMNAATM | |
| SCHEMBL29519306 | 0.83 | MAPT (0.80) | MAPTMEN1KMT2ALMNAATM | |
| SCHEMBL30600488 | 0.80 | MAPT (0.83) | MAPTMEN1KMT2ALMNAATM | |
| SCHEMBL155568 | 0.80 | MAPT (0.83) | MAPTMEN1KMT2ALMNAATM | |
| SCHEMBL7979640 | 0.80 | MAPT (0.83) | MAPTMEN1KMT2ALMNAATM | |
| Nitric Acid SCHEMBL31591113 | 0.78 | GPR3 (0.67) | MAPTMEN1KMT2ALMNAATM | |
| SCHEMBL28297109 | 0.78 | MAPT (0.59) | MAPTMEN1KMT2ALMNAATM | |
| Hydrochloric Acid SCHEMBL28297111 | 0.77 | MAPT (0.58) | MAPTMEN1KMT2ALMNAATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109851550-A | 7- aminocarbazole sulfamide derivative and its preparation method and application | 中国医学科学院医药生物技术研究所 | 2019-06-07 | — | — | CN | disclosed |
| WO-2017093718-A1 | 1-CYANO-PYRROLIDINE DERIVATIVES AS INHIBITORS OF USP30. | MISSION THERAPEUTICS LIMITED (GB) | 2017-06-08 | — | — | WO | disclosed |