⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL157942 | 0.64 | — | — | |
| SCHEMBL23774760 | 0.62 | — | — | |
| SCHEMBL9093680 | 0.60 | — | — | |
| SCHEMBL5838552 | 0.59 | — | — | |
| SCHEMBL30767406 | 0.58 | CHRNB4 (0.32) | — | |
| SCHEMBL2418026 | 0.58 | — | — | |
| SCHEMBL4573276 | 0.57 | — | — | |
| SCHEMBL4328618 | 0.57 | — | — | |
| SCHEMBL13355549 | 0.57 | NOS3 (0.32) | — | |
| SCHEMBL10057749 | 0.57 | NOS3 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11530194-B2 | Amide compounds and method for making and using | RIGEL PHARMACEUTICALS, INC. (US) | 2022-12-20 | — | — | US | disclosed |
| US-20210214342-A1 | AMIDE COMPOUNDS AND METHOD FOR MAKING AND USING | RIGEL PHARMACEUTICALS, INC. (US) | 2021-07-15 | — | — | US | disclosed |
| CN-110494453-A | Anti- trypsinlike enzyme antibody, its composition and application thereof | HOFFMANN LA ROCHE | 2019-11-22 | — | — | CN | disclosed |
| CN-110256567-A | For selecting and generating the stereotropic method of customization target and application thereof containing at least two different binding entities | 弗·哈夫曼-拉罗切有限公司 | 2019-09-20 | — | — | CN | disclosed |
| CN-106323875-B | Sample uses maximized system and method | 西拉诺斯知识产权有限责任公司 | 2019-07-09 | — | — | CN | disclosed |
| CN-108333379-A | Modular point-of-care devices and its application | 赛拉诺斯知识产权有限责任公司 | 2018-07-27 | — | — | CN | disclosed |
| CN-104619715-B | Method for the production and selection of molecules comprising at least two different entities and uses thereof | 弗·哈夫曼-拉罗切有限公司 | 2018-06-05 | — | — | CN | disclosed |
| CN-108026180-A | Anti- hydroxyl putrescine lysine antibody and application thereof | 豪夫迈·罗氏有限公司 | 2018-05-11 | — | — | CN | disclosed |
| CN-107973856-A | The Ag-Ab conjugate of covalent attachment | 弗·哈夫曼-拉罗切有限公司 | 2018-05-01 | — | — | CN | disclosed |
| CN-104508133-B | Methods for producing monomeric and multimeric molecules and uses thereof | 弗·哈夫曼-拉罗切有限公司 | 2018-04-20 | — | — | CN | disclosed |
| CN-103323610-A | Modular point-of-care devices, and uses thereof | THERANOS INC | 2013-09-25 | — | — | CN | disclosed |
| CN-101121021-B | Humanized anti-ErbB2 antidbodies and treatment with anti-ErbB2 antibodies | GENENTECH INC. (US) | 2011-12-07 | — | — | CN | disclosed |
| CN-102170909-A | Anti-NOTCH2 antibodies and methods of use | HOFFMANN LA ROCHE | 2011-08-31 | — | — | CN | disclosed |
| CN-101874205-A | Modular point-of-care devices and applications thereof | THERANOS INC | 2010-10-27 | — | — | CN | disclosed |
| CN-1726394-B | Sets of digital antibodies directed against short epitopes, and methods using same | ABMETRIX INC | 2010-10-13 | — | — | CN | disclosed |
| CN-101121021-A | Humanized anti-ErbB2 antidbodies and treatment with anti-ErbB2 antibodies | GENENTECH INC (US) | 2008-02-13 | — | — | CN | disclosed |
| CN-1726394-A | Sets of digital antibodies directed against short epitopes, and methods using same | ABMETRIX INC (US) | 2006-01-25 | — | — | CN | disclosed |
| CN-1125374-C | Photothermographic material and method for making | FUJI PHOTO FILM CO LTD (JP) | 2003-10-22 | — | — | CN | disclosed |
| CN-1370082-A | Humanized anti-ErbB 2 antibodies and treatment with anti-ErbB 2 antibodies | GENENTECH INC (US) | 2002-09-18 | — | — | CN | disclosed |
| CN-1168482-A | Photothermographic material and method for making | FUJI PHOTO FILM CO LTD (JP) | 1997-12-24 | — | — | CN | disclosed |