Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.50 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 2/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11962323 | 0.98 | SMN1; SMN2 (0.54) | KDM4EGLAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL27388761 | 0.98 | SMN1; SMN2 (0.54) | KDM4EGLAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL27284020 | 0.98 | SMN1; SMN2 (0.54) | KDM4EGLAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL12093737 | 0.96 | KDM4E (0.47) | KDM4EGLAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL1610503 | 0.91 | TNKS (0.48) | KDM4EGLAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL20037855 | 0.84 | CYP2D6 (0.50) | — | |
| SCHEMBL15448506 | 0.84 | ESR2 (0.50) | KDM4EGLAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL12975623 | 0.82 | HTR2C (0.47) | — | |
| SCHEMBL19088565 | 0.82 | TNKS (0.43) | KDM4EGLAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL18291382 | 0.82 | CYP2D6 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022174253-A1 | HPK1 ANTAGONISTS AND USES THEREOF | Nimbus Saturn, Inc. (US) | 2022-08-18 | — | — | WO | disclosed |
| US-20200287143-A1 | ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME | LG CHEM, LTD. (KR) | 2020-09-10 | — | — | US | disclosed |
| US-20180044343-A1 | BICYCLIC IMIDAZOLO DERIVATIVE | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2018-02-15 | — | — | US | disclosed |
| EP-2338882-B1 | 2-((6-(Haloalkyl substituted))pyridin-3-yl)-tetrahydro-1H-1(lamba)4-thien-1-ylidenecyanamide derivatives and related compounds as pesticides and insecticides | DOW AGROSCIENCES LLC (US) | 2017-06-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180044343-A1 | BICYCLIC IMIDAZOLO DERIVATIVE | PDE3A, PDE2A, PDE5A | KDM4E 2496/4885GLA 587/4885HTT 4781/4885 |
| US-20200287143-A1 | ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME | SCO2, RER1, ORC3 | KDM4E 2951/4885GLA 2407/4885HTT 3412/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.