Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18596353 | 0.95 | TSHR (0.37) | TSHRLMNAGPR119ALDH1A1MAPT | |
| SCHEMBL18930258 | 0.92 | TSHR (0.35) | TSHRLMNAALDH1A1MAPTNPSR1 | |
| SCHEMBL18930259 | 0.92 | TSHR (0.35) | TSHRLMNAALDH1A1MAPTNPSR1 | |
| SCHEMBL18925912 | 0.92 | TSHR (0.35) | TSHRLMNAALDH1A1MAPTNPSR1 | |
| SCHEMBL2756462 | 0.86 | TSHR (0.38) | TSHRLMNAALDH1A1MAPTNPSR1 | |
| SCHEMBL12705306 | 0.86 | TSHR (0.38) | TSHRLMNAALDH1A1MAPTNPSR1 | |
| SCHEMBL12016860 | 0.86 | TSHR (0.38) | TSHRLMNAALDH1A1MAPTNPSR1 | |
| SCHEMBL18596352 | 0.84 | TSHR (0.37) | TSHRLMNAGPR119ALDH1A1MAPT | |
| SCHEMBL18596139 | 0.82 | TP53 (0.34) | TSHRLMNAGPR119ALDH1A1MAPT | |
| SCHEMBL18653227 | 0.82 | TP53 (0.34) | TSHRLMNAGPR119ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10039754-B2 | Anti-viral compounds | ABBVIE INC. (US) | 2018-08-07 | — | — | US | disclosed |
| US-20170157104-A1 | Anti-Viral Compounds | ABBVIE INC. (US) | 2017-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170157104-A1 | Anti-Viral Compounds | HAVCR2, EIF2AK2, MAVS | TSHR 4834/4885LMNA 3118/4885GPR119 3832/4885 |
| US-10039754-B2 | Anti-viral compounds | HAVCR2, EIF2AK2, MAVS | TSHR 4834/4885LMNA 3118/4885GPR119 3832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.