Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 3/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 5/20 | 0.35 |
| ▸ | DRD2 | P14416 | 4/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 4/20 | 0.34 |
| ▸ | DRD4 | P21917 | 3/20 | 0.34 |
| ▸ | HTR2A | P28223 | 3/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.34 |
| ▸ | HRH2 | P25021 | 3/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.34 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18930771 | 0.88 | ATM (0.43) | KCNH2KCNJ1ITGB3ITGA2BSLC1A2 | |
| SCHEMBL18930522 | 0.81 | ATM (0.43) | KCNH2SLC1A2SLC1A3DRD2P2RX7 | |
| SCHEMBL18930525 | 0.80 | ACACB (0.45) | KCNH2ACACBP2RX7HRH1HRH2 | |
| SCHEMBL21144688 | 0.80 | KCNH2 (0.46) | KCNH2KCNJ1ITGB3ITGA2BSLC1A2 | |
| SCHEMBL21144685 | 0.80 | KCNH2 (0.46) | KCNH2KCNJ1ITGB3ITGA2BSLC1A2 | |
| SCHEMBL21144891 | 0.76 | ATM (0.40) | DRD2P2RX7HRH1HRH2 | |
| SCHEMBL21144890 | 0.76 | ATM (0.40) | DRD2P2RX7HRH1HRH2 | |
| SCHEMBL21169852 | 0.76 | GPR119 (0.42) | DRD2P2RX7HRH1HRH2 | |
| SCHEMBL18930773 | 0.76 | GPR119 (0.42) | DRD2P2RX7HRH1HRH2 | |
| SCHEMBL21144689 | 0.76 | ATM (0.40) | DRD2P2RX7HRH1HRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3383865-B1 | FURANE DERIVATIVES AS INHIBITORS OF ATAD2 | Bayer Pharma AG (DE) | 2020-01-29 | — | — | EP | disclosed |
| WO-2017093272-A1 | FURANE DERIVATIVES AS INHIBITORS OF ATAD2 | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-06-08 | — | — | WO | disclosed |