Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | NPY4R | P50391 | 4/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.39 |
| ▸ | NPY1R | P25929 | 3/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | TLR2 | O60603 | 1/20 | 0.35 |
| ▸ | GNPAT | O15228 | 1/20 | 0.35 |
| ▸ | CCKBR | P32239 | 2/20 | 0.35 |
| ▸ | NMT2 | O60551 | 1/20 | 0.35 |
| ▸ | NMT1 | P30419 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17722910 | 1.00 | PTGS1 (0.46) | PTGS1PTGS2ITGB3ITGA2BPTPN1 | |
| SCHEMBL20889018 | 0.91 | PTGS1 (0.45) | PTGS1PTGS2ITGB3ITGA2BPTPN1 | |
| SCHEMBL21474404 | 0.91 | PTGS1 (0.45) | PTGS1PTGS2ITGB3ITGA2BPTPN1 | |
| SCHEMBL19681467 | 0.91 | PTGS1 (0.45) | PTGS1PTGS2ITGB3ITGA2BPTPN1 | |
| SCHEMBL18909028 | 0.91 | PTGS1 (0.45) | PTGS1PTGS2ITGB3ITGA2BPTPN1 | |
| SCHEMBL22694944 | 0.91 | PTGS1 (0.46) | PTGS1PTGS2ITGB3ITGA2BPTPN1 | |
| SCHEMBL17722904 | 0.91 | NMT1 (0.45) | PTGS1PTGS2NPY4RNPY5RNPY1R | |
| SCHEMBL20864073 | 0.90 | PTGS1 (0.44) | PTGS1PTGS2ITGB3ITGA2BPTPN1 | |
| SCHEMBL22668929 | 0.90 | PTGS1 (0.44) | PTGS1PTGS2ITGB3ITGA2BPTPN1 | |
| SCHEMBL17722906 | 0.89 | NMT1 (0.48) | NPY4RNPY5RNPY1RNPY2RROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017095805-A1 | ANTI-huLRRC15 ANTIBODY DRUG CONJUGATES AND METHODS FOR THEIR USE | ABBVIE INC. (US) | 2017-06-08 | — | — | WO | disclosed |