Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.40 |
| ▸ | NPY4R | P50391 | 4/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.36 |
| ▸ | NPY1R | P25929 | 3/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.34 |
| ▸ | FNTB | P49356 | 1/20 | 0.34 |
| ▸ | NMT2 | O60551 | 1/20 | 0.33 |
| ▸ | NMT1 | P30419 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17722910 | 0.91 | PTGS1 (0.46) | PTGS1PTGS2PTPN1ITGB3ITGA2B | |
| SCHEMBL18932741 | 0.91 | PTGS1 (0.46) | PTGS1PTGS2PTPN1ITGB3ITGA2B | |
| SCHEMBL18909028 | 0.89 | PTGS1 (0.45) | PTGS1PTGS2PTPN1ITGB3ITGA2B | |
| SCHEMBL20889018 | 0.89 | PTGS1 (0.45) | PTGS1PTGS2PTPN1ITGB3ITGA2B | |
| SCHEMBL21474404 | 0.89 | PTGS1 (0.45) | PTGS1PTGS2PTPN1ITGB3ITGA2B | |
| SCHEMBL19681467 | 0.89 | PTGS1 (0.45) | PTGS1PTGS2PTPN1ITGB3ITGA2B | |
| SCHEMBL20864073 | 0.88 | PTGS1 (0.44) | PTGS1PTGS2PTPN1ITGB3ITGA2B | |
| SCHEMBL22668929 | 0.88 | PTGS1 (0.44) | PTGS1PTGS2PTPN1ITGB3ITGA2B | |
| SCHEMBL21034050 | 0.86 | C3AR1 (0.38) | PTGS1PTGS2NPY4RNPY5RNPY1R | |
| SCHEMBL1325459 | 0.84 | C3AR1 (0.48) | PTGS1PTGS2C3AR1FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020236797-A1 | VARIANT CD58 DOMAINS AND USES THEREOF | NOVARTIS AG (CH) | 2020-11-26 | — | — | WO | disclosed |
| WO-2020236795-A2 | TRISPECIFIC BINDING MOLECULES AGAINST BCMA AND USES THEREOF | NOVARTIS AG (CH) | 2020-11-26 | — | — | WO | disclosed |