SCHEMBL18935458

SCHEMBL18935458

C1=CN=c2ccccc2=CN=1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5050144 0.73
SCHEMBL5050151 0.73
SCHEMBL16690908 0.73
Quinazoline SCHEMBL5922743 0.65
SCHEMBL15619554 0.64
SCHEMBL8527502 0.64
SCHEMBL18949173 0.63
SCHEMBL18744839 0.63
SCHEMBL18744829 0.63
SCHEMBL4795506 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 922 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025111482-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS BEXSON BIOMEDICAL, INC. (US) 2025-05-30 WO claimed
US-20250073207-A1 PSILOCIN BENZOATE FORMULATION FOR INTRAVENOUS INFUSION ELEUSIS THERAPEUTICS US, INC. 2025-03-06 US claimed
WO-2024127333-A1 CYTOTOXIC COMPOUNDS PHEON THERAPEUTICS LTD (GB) 2024-06-20 WO claimed
CN-117263873-A 1, 4-benzodiazepine compounds and application thereof in preparation of antitumor drugs 复旦大学 2023-12-22 CN claimed
WO-2023241738-A2 1,4-BENZODIAZEPINE COMPOUND AND USE THEREOF IN PREPARATION OF ANTI-TUMOR DRUG 复旦大学 2023-12-21 WO claimed
US-20230277568-A1 METHOD OF TREATMENT FOR PSILOCYBIN OR PSILOCIN INFUSION ELEUSIS THERAPEUTICS US, INC. 2023-09-07 US claimed
CN-115925642-A Synthesis method of 1, 4-benzodiazepine heterocyclic derivative 枣庄学院 2023-04-07 CN claimed
CN-115368371-A Chiral triazine heterocyclic spiro-conjugated 1, 4-benzodiazepine-2-one compound and preparation method thereof 北京工业大学 2022-11-22 CN claimed
CN-112851691-B Chiral oxadiazine heterocyclic compound and preparation method thereof 北京工业大学 2022-10-11 CN claimed
CN-112574220-B Chiral heterocyclic compound and preparation method thereof 北京工业大学 2022-10-11 CN claimed
EP-0024272-B1 1,4-BENZODIAZEPINES AND THEIR SALTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM Kali-Chemie Pharma GmbH (DE) 1982-12-08 EP claimed
US-4362732-A Diazepine derivatives and their use HOFFMANN-LA ROCHE INC. (US) 1982-12-07 US claimed
US-4352818-A ANTIDOTES FOR INTOXICATION CAUSED BY 1,4-BENZODIAZEPINE TRANQUILIZERS HOFFMANN-LA ROCHE INC. (US) 1982-10-05 US claimed
US-4352817-A ANTIDOTE FOR TRANQUILLIZING EFFECTS OF 1,4-BENZODIAZEPINES HOFFMANN-LA ROCHE INC. (US) 1982-10-05 US claimed
US-4338314-A [1,2]Anellated-7-phenyl-1,4-benzodiazepine and pharmaceutical compositions thereof and use for treatment of ulcers KALI-CHEMIE PHARMA GMBH (DE) 1982-07-06 US claimed
US-4316897-A TRANQUILIZERS HOFFMANN-LA ROCHE INC. (US) 1982-02-23 US claimed
US-4170649-A 2-SUBSTITUTED BY CYANOMETHYLENE OR CARBAMOYLMETHYLENE, TRANQUILIZERS, OXIDIZING CORRESPONDING CYANOMETHYL COMPOUNDS, OPTIONAL HYDROLYSIS KALI-CHEMIE PHARMA GMBH (DE) 1979-10-09 US claimed
US-4155904-A Process for the preparation of 1,4-benzo-diazepines and 1,4-benzodiazepinones SCHERING CORPORATION (US) 1979-05-22 US claimed
US-4145417-A TRANQUILIZERS, SEDATIVES, HYPNOTICS, ADDUCTS WITH ALDEHYDES DDSA PHARMACEUTICLAS LTD. (GB) 1979-03-20 US claimed
US-4083948-A IODINE LABELS HOFFMANN-LA ROCHE, INC. (US) 1978-04-11 US claimed