Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.43 |
| ▸ | ADH1B | P00325 | 2/20 | 0.43 |
| ▸ | ADH1C | P00326 | 2/20 | 0.43 |
| ▸ | ADH1A | P07327 | 2/20 | 0.43 |
| ▸ | ADH7 | P40394 | 2/20 | 0.43 |
| ▸ | ADH4 | P08319 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18935657 | 1.00 | TSHR (0.59) | TSHRALDH1A1S1PR2S1PR4S1PR1 | |
| SCHEMBL18935659 | 1.00 | TSHR (0.59) | TSHRALDH1A1S1PR2S1PR4S1PR1 | |
| SCHEMBL18935661 | 1.00 | TSHR (0.59) | TSHRALDH1A1S1PR2S1PR4S1PR1 | |
| SCHEMBL18935655 | 1.00 | TSHR (0.59) | TSHRALDH1A1S1PR2S1PR4S1PR1 | |
| SCHEMBL18935662 | 1.00 | TSHR (0.59) | TSHRALDH1A1S1PR2S1PR4S1PR1 | |
| SCHEMBL11420227 | 0.98 | TSHR (0.55) | TSHRALDH1A1S1PR2S1PR4S1PR1 | |
| SCHEMBL19442039 | 0.98 | TSHR (0.62) | TSHRALDH1A1S1PR2S1PR4S1PR1 | |
| SCHEMBL19442178 | 0.98 | TSHR (0.62) | TSHRALDH1A1S1PR2S1PR4S1PR1 | |
| SCHEMBL19442065 | 0.95 | TSHR (0.65) | TSHRALDH1A1S1PR2S1PR4S1PR1 | |
| SCHEMBL24013256 | 0.93 | TSHR (0.62) | TSHRALDH1A1S1PR2S1PR4S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10407636-B2 | Dialkylaminoalkanol friction modifiers for fuels and lubricants | AFTON CHEMICAL CORPORATION (US) | 2019-09-10 | — | — | US | disclosed |
| US-20180127675-A1 | DIALKYLAMINOALKANOL FRICTION MODIFIERS FOR FUELS AND LUBRICANTS | AFTON CHEMICAL CORPORATION | 2018-05-10 | — | — | US | disclosed |
| US-9873849-B2 | Dialkyaminoalkanol friction modifiers for fuels and lubricants | AFTON CHEMICAL CORPORATION (US) | 2018-01-23 | — | — | US | disclosed |
| US-20170166826-A1 | Dialkyaminoalkanol Friction Modifiers For Fuels And Lubricants | AFTON CHEMICAL CORPORATION | 2017-06-15 | — | — | US | disclosed |
| EP-3178909-A1 | DIALKYLAMINOALKANOL FRICTION MODIFIERS FOR FUELS AND LUBRICANTS | Afton Chemical Corporation (US) | 2017-06-14 | — | — | EP | disclosed |