Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | ADH1B | P00325 | 1/20 | 0.39 |
| ▸ | ADH1C | P00326 | 1/20 | 0.39 |
| ▸ | ADH1A | P07327 | 1/20 | 0.39 |
| ▸ | ADH4 | P08319 | 1/20 | 0.39 |
| ▸ | ADH7 | P40394 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19442065 | 0.98 | TSHR (0.65) | TSHRALDH1A1CYP2C19CYP1A2MEN1 | |
| SCHEMBL19442178 | 0.95 | TSHR (0.62) | TSHRALDH1A1CYP2C19CYP1A2S1PR2 | |
| SCHEMBL19442039 | 0.95 | TSHR (0.62) | TSHRALDH1A1CYP2C19CYP1A2S1PR2 | |
| SCHEMBL18935662 | 0.93 | TSHR (0.59) | TSHRALDH1A1CYP2C19CYP1A2MEN1 | |
| SCHEMBL18935663 | 0.93 | TSHR (0.59) | TSHRALDH1A1CYP2C19CYP1A2MEN1 | |
| SCHEMBL18935655 | 0.93 | TSHR (0.59) | TSHRALDH1A1CYP2C19CYP1A2MEN1 | |
| SCHEMBL18935661 | 0.93 | TSHR (0.59) | TSHRALDH1A1CYP2C19CYP1A2MEN1 | |
| SCHEMBL18935657 | 0.93 | TSHR (0.59) | TSHRALDH1A1CYP2C19CYP1A2MEN1 | |
| SCHEMBL18935659 | 0.93 | TSHR (0.59) | TSHRALDH1A1CYP2C19CYP1A2MEN1 | |
| SCHEMBL18553116 | 0.93 | TSHR (0.50) | TSHRALDH1A1CYP2C19CYP1A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210348169-A1 | METHODS FOR TREATING AGING AND SKIN DISORDERS USING NUCLEIC ACIDS TARGETING TYR OR MMP1 | PHIO PHARMACEUTICALS CORP. (US) | 2021-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210348169-A1 | METHODS FOR TREATING AGING AND SKIN DISORDERS USING NUCLEIC ACIDS TARGETING TYR OR MMP1 | MMP1, MMP3, MMP11 | TSHR 3827/4885ALDH1A1 1541/4885CYP2C19 4841/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.