Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLA | Q9Y4D2 | 9/20 | 1.00 |
| ▸ | DAGLB | Q8NCG7 | 7/20 | 1.00 |
| ▸ | DDHD2 | O94830 | 1/20 | 0.55 |
| ▸ | AHR | P35869 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18935852 | 0.91 | DAGLA (1.00) | DAGLADAGLBDDHD2 | |
| SCHEMBL18935831 | 0.90 | DAGLA (1.00) | DAGLADAGLBDDHD2ADRB2ADRB1 | |
| SCHEMBL18935782 | 0.87 | DAGLA (1.00) | DAGLADAGLBDDHD2AHRCYP3A4 | |
| SCHEMBL18935826 | 0.84 | DAGLA (0.72) | DAGLADAGLBDDHD2AHRCYP3A4 | |
| SCHEMBL20576133 | 0.80 | DAGLA (0.66) | DAGLADAGLBDDHD2AHRCYP3A4 | |
| SCHEMBL18935851 | 0.78 | DAGLA (1.00) | DAGLADAGLBDDHD2 | |
| SCHEMBL18921268 | 0.78 | DAGLB (1.00) | DAGLADAGLBDDHD2AHRADRB2 | |
| SCHEMBL18935850 | 0.77 | DAGLA (1.00) | DAGLADAGLBDDHD2 | |
| SCHEMBL18935859 | 0.73 | DAGLA (1.00) | DAGLADAGLBDDHD2 | |
| SCHEMBL20576782 | 0.73 | DAGLA (0.69) | DAGLADAGLBDDHD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017096315-A1 | TRIAZOLE DAGL(α) INHIBITORS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2017-06-08 | — | — | WO | disclosed |