Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18936250 | 1.00 | MEN1 (0.34) | MEN1GAAKMT2AADRB2ADRB1 | |
| SCHEMBL15791723 | 0.91 | NPC1 (0.34) | MEN1GAAKMT2AADRB2ADRB1 | |
| SCHEMBL15791722 | 0.91 | NPC1 (0.34) | MEN1GAAKMT2AADRB2ADRB1 | |
| SCHEMBL17709434 | 0.85 | CYP2D6 (0.36) | ADRB2ADRB1ADRB3 | |
| SCHEMBL16711537 | 0.84 | MEN1 (0.40) | MEN1GAAKMT2ALMNA | |
| SCHEMBL15528058 | 0.76 | RAB9A (0.42) | ADRB2ADRB1ADRB3NPC1RAB9A | |
| SCHEMBL6625123 | 0.74 | POLB (0.41) | MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL16709051 | 0.73 | TSHR (0.30) | — | |
| SCHEMBL14365667 | 0.73 | TSHR (0.30) | — | |
| SCHEMBL28627606 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2986607-B1 | ANTIBACTERIAL BIAROMATIC DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2017-06-14 | — | — | EP | disclosed |