Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FSCN1 | Q16658 | 1/20 | 0.53 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 7/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | BUB1 | O43683 | 1/20 | 0.38 |
| ▸ | CPT1A | P50416 | 1/20 | 0.37 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30695022 | 0.89 | FSCN1 (0.68) | FSCN1GRM5KMT2APTGER4HDAC1 | |
| SCHEMBL17038822 | 0.89 | FSCN1 (0.68) | FSCN1GRM5KMT2APTGER4HDAC1 | |
| SCHEMBL17199339 | 0.85 | FSCN1 (0.55) | FSCN1KMT2APTGER4CPT1A | |
| SCHEMBL18937454 | 0.82 | FSCN1 (0.59) | FSCN1PTGER4HDAC1HDAC10HDAC6 | |
| SCHEMBL17199362 | 0.82 | FSCN1 (0.56) | FSCN1KMT2APTGER4HDAC1HDAC10 | |
| SCHEMBL17199424 | 0.82 | FSCN1 (0.53) | FSCN1PTGER4HDAC1HDAC10HDAC6 | |
| SCHEMBL17199347 | 0.82 | FSCN1 (0.60) | FSCN1PTGER4HDAC1HDAC10HDAC6 | |
| SCHEMBL17199318 | 0.80 | FSCN1 (0.54) | FSCN1PTGER4HDAC1HDAC10HDAC6 | |
| SCHEMBL18937544 | 0.80 | FSCN1 (0.52) | FSCN1KMT2APTGER4HDAC6HDAC3 | |
| SCHEMBL17199346 | 0.80 | FSCN1 (0.58) | FSCN1KMT2APTGER4HDAC1HDAC10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170158692-A1 | COMPOUNDS AND METHODS FOR INHIBITING FASCIN | CORNELL UNIVERSITY | 2017-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170158692-A1 | COMPOUNDS AND METHODS FOR INHIBITING FASCIN | FSCN1, MTPN, MYOF | FSCN1 1/4885GRM5 1986/4885KMT2A 4757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.