MYOF

Myoferlin · Q9NZM1 · MYOF on Sugi Atlas →

265 patent compounds predicted against MYOF, 161 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL31519075 SCHEMBL31519075 1.00 2/20
SCHEMBL31519091 SCHEMBL31519091 0.98 2/20
SCHEMBL31519121 SCHEMBL31519121 0.98 2/20
SCHEMBL31519102 SCHEMBL31519102 0.95 2/20
SCHEMBL31519107 SCHEMBL31519107 0.91 2/20
SCHEMBL31519105 SCHEMBL31519105 0.89 2/20
SCHEMBL31519117 SCHEMBL31519117 0.86 2/20
SCHEMBL31519108 SCHEMBL31519108 0.85 2/20
SCHEMBL31519090 SCHEMBL31519090 0.85 2/20
SCHEMBL31519103 SCHEMBL31519103 0.85 2/20
SCHEMBL31519097 SCHEMBL31519097 0.84 2/20
SCHEMBL31519112 SCHEMBL31519112 0.84 2/20
SCHEMBL31519074 SCHEMBL31519074 0.84 2/20
SCHEMBL31519083 SCHEMBL31519083 0.84 2/20
SCHEMBL31519087 SCHEMBL31519087 0.83 2/20
SCHEMBL31519089 SCHEMBL31519089 0.83 2/20
SCHEMBL31519094 SCHEMBL31519094 0.83 2/20
SCHEMBL31519110 SCHEMBL31519110 0.83 2/20
SCHEMBL31519114 SCHEMBL31519114 0.83 2/20
SCHEMBL31519092 SCHEMBL31519092 0.82 2/20

Clinical trials — most relevant to MYOF by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Deflazacort in Dysferlinopathies PHASE2/PHASE3COMPLETED
A Clinical Study to Evaluate the Safety, Tolerability, and Efficacy of BBM-D101 in the Treatment of Duchenne Muscular Dystrophy. PHASE1/PHASE2RECRUITING
Evaluation of the Safety and Efficacy of BBM-D101 to Treat Patients with Duchenne Muscular Dystrophy EARLY_PHASE1RECRUITING
Influence of Sarcopenia on the Course of the Diseases nanRECRUITING
Observational Cohort Study of Dysferlinopathy in China nanCOMPLETED
ACTLIFE: is Active Life-style Enough? nanUNKNOWN
Clinical Outcome Study for Dysferlinopathy nanUNKNOWN
Transcutaneous Functional Magnetic Muscle Stimulation in Critically Ill nanUNKNOWN
Myostatin and Irisin Levels in Predicting the Outcome of Patients With Systemic Inflammation: A Prospective Observational Study nanCOMPLETED
Molecular and Genetic Studies of Congenital Myopathies nanRECRUITING
High-definition Surface Electromyography Markers for the Diagnosis of Sarcopenia nanRECRUITING
Comparison of Serum Myokine Dosages and Imaging Methods in the Evaluation of Sarcopenia in Patients With Hepatocellular Carcinoma nanRECRUITING
High-definition Surface Electromyography Markers for the Diagnosis and Monitoring of Sarcopenia nanRECRUITING
Skeletal Muscle Regeneration in Survivors of Critical Illness: How to Prevent Satellite Cell Failure? nanRECRUITING
The Effect of Blood Flow Restriction (Bfr) Exercise on Acute Systemic Myokine Levels in Healthy Trained Men nanUNKNOWN
Characteristics of Nondystrophic Myotonias nanCOMPLETED
Myotubular and Centronuclear Myopathy Patient Registry nanRECRUITING
Muscle Tissue Bank for Muscular Dystrophy nanCOMPLETED
The Relationship Between Myonectin Concentration and the Course of ST-segment Elevation Myocardial Infarction nanUNKNOWN
Natural History Study for Patients With Nemaline Myopathy in Belgium nanNOT_YET_RECRUITING
GDF-15 as a Biomarker for Mitochondrial Disease nanCOMPLETED
Beta-Hydroxy-Beta-Methylbutyrate Supplementation and Physical Activity in Liver Cirrhosis: a Controlled Trial nanUNKNOWN
Chronic Muscle Disuse in the Elderly nanCOMPLETED
Protein Intake and Step Reduction in Older Adults nanCOMPLETED
Exploring Novel Biomarkers of ICU-AW in Mechanically Ventilated Children at the Molecular Level nanENROLLING_BY_INVITATION
Phenotype - Genotype Correlation in a Sample of Egyptian Patients With Congenital Myopathies and Congenital Muscular Dystrophies nanRECRUITING
Effect of Exercise on the Human Skeletal Muscle Phosphoproteome nanCOMPLETED
Beta-Hydroxy-Beta-Methylbutyrate (HMB) Supplementation After Liver Transplantation nanCOMPLETED
Study of Genotype and Phenotype Characterization in Duchenne Muscular Dystrophy With Small Mutations nanUNKNOWN
Reduction of Muscle Catabolism Through Brain Activation in Burn Patients nanNOT_YET_RECRUITING

Related proteins — ESM-2 sequence neighbours (a MYOF binder may also engage these)

ProteinNameSimilarity
Q69ZN7 1.000 Q69ZN7 →
A0AB32U2W5 0.997 A0AB32U2W5 →
O75923 0.996 O75923 →
B3DLH6 0.996 B3DLH6 →
A6QQP7 0.992 A6QQP7 →
Q9ESD7 0.990 Q9ESD7 →
Q2WGJ9 0.990 Q2WGJ9 →
E0CZ42 0.988 E0CZ42 →
A0AVI2 0.987 A0AVI2 →
P0DM40 0.984 P0DM40 →
A1ZBD6 0.983 A1ZBD6 →
Q9H1H9 0.983 Q9H1H9 →
NFKB1 Nuclear factor NF-kappa-B p105 subunit 0.981 landscape →
Q2KHZ2 0.981 Q2KHZ2 →
KDM5B Lysine-specific demethylase 5B 0.981 landscape →
Q12466 0.981 Q12466 →
Q9EQW7 0.980 Q9EQW7 →
F4J8C6 0.980 F4J8C6 →
Q94CF0 0.980 Q94CF0 →
Q8BX57 0.980 Q8BX57 →
Q3UMY5 0.980 Q3UMY5 →
P31669 0.980 P31669 →
Q69ZS7 0.980 Q69ZS7 →
Q17388 0.980 Q17388 →
Q5ZMN2 0.980 Q5ZMN2 →
P43125 0.980 P43125 →
Q6AXM7 0.980 Q6AXM7 →
A1ZAJ2 0.980 A1ZAJ2 →
Q6DIP5 0.980 Q6DIP5 →
Q5XHF8 0.980 Q5XHF8 →