SCHEMBL1893741

SCHEMBL1893741

c1ccc(C2CNC(c3ccccc3)CN2)cc1

nearest known ligand 0.54

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PRCP P42785 1/20 0.50
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
GBA1 P04062 1/20 0.45
SLC18A3 Q16572 1/20 0.41
SIGMAR1 Q99720 1/20 0.41
TSHR P16473 1/20 0.40
NPC1 O15118 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15670538 1.00 PRCP (0.50) PRCPMEN1KMT2AGBA1SLC18A3
SCHEMBL8535631 0.97
SCHEMBL369386 0.97
SCHEMBL1688451 0.97
Ammonia Solution, Strong SCHEMBL28071164 0.94 PRCP (0.50) PRCPMEN1KMT2AGBA1SLC18A3
SCHEMBL14972873 0.94 PRCP (0.50) PRCPMEN1KMT2AGBA1SLC18A3
SCHEMBL15531917 0.87 PRCP (0.41) PRCPMEN1KMT2AGBA1
SCHEMBL29060454 0.87 GBA1 (0.46) PRCPMEN1KMT2AGBA1SLC18A3
SCHEMBL10990501 0.87 PRCP (0.41) PRCPMEN1KMT2AGBA1
SCHEMBL15531918 0.87 PRCP (0.41) PRCPMEN1KMT2AGBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011055247-A1 A SYNTHETIC CYCLIC DIPEPTIDE AND A PROCESS THEREOF JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH (IN) 2011-05-12 WO claimed
CN-119120612-A Method for synthesizing piperazine and derivatives thereof through double-enzyme cascade catalysis 南京工业大学 2024-12-13 CN disclosed
WO-2011055247-A1 A SYNTHETIC CYCLIC DIPEPTIDE AND A PROCESS THEREOF JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH (IN) 2011-05-12 WO disclosed
US-7217447-B2 Ink-jet recording sheet FUJIFILM CORPORATION (JP) 2007-05-15 US disclosed
US-7217447-B2 Ink-jet recording sheet FUJIFILM CORPORATION (JP) 2007-05-15 US disclosed
US-4695383-A COPOLYAMIDE FROM A DIAMINODIPHENYL SULFONE TOYO BOSEKI KABUSHIKI KAISHA (JP) 1987-09-22 US disclosed