SCHEMBL15670538

SCHEMBL15670538

c1ccc([C@@H]2CN[C@H](c3ccccc3)CN2)cc1

nearest known ligand 0.54

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PRCP P42785 1/20 0.50
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
GBA1 P04062 1/20 0.45
SLC18A3 Q16572 1/20 0.41
SIGMAR1 Q99720 1/20 0.41
TSHR P16473 1/20 0.40
NPC1 O15118 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1893741 1.00 PRCP (0.50) PRCPMEN1KMT2AGBA1SLC18A3
SCHEMBL8535631 0.97
SCHEMBL369386 0.97
SCHEMBL1688451 0.97
Ammonia Solution, Strong SCHEMBL28071164 0.94 PRCP (0.50) PRCPMEN1KMT2AGBA1SLC18A3
SCHEMBL14972873 0.94 PRCP (0.50) PRCPMEN1KMT2AGBA1SLC18A3
SCHEMBL15531917 0.87 PRCP (0.41) PRCPMEN1KMT2AGBA1
SCHEMBL29060454 0.87 GBA1 (0.46) PRCPMEN1KMT2AGBA1SLC18A3
SCHEMBL10990501 0.87 PRCP (0.41) PRCPMEN1KMT2AGBA1
SCHEMBL15531918 0.87 PRCP (0.41) PRCPMEN1KMT2AGBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9701684-B2 Chiral fluorinating reagents OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2017-07-11 US disclosed
US-20150284401-A1 CHIRAL FLUORINATING REAGENTS OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2015-10-08 US disclosed
EP-2914582-A2 CHIRAL FLUORINATING REAGENTS Isis Innovation Limited (GB) 2015-09-09 EP disclosed
WO-2014068341-A2 CHIRAL FLUORINATING REAGENTS ISIS INNOVATION LIMITED (GB) 2014-05-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150284401-A1 CHIRAL FLUORINATING REAGENTS TIAM1, AFF2, AFF1 PRCP 4687/4885MEN1 1062/4885KMT2A 3049/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.