Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 10/20 | 0.52 |
| ▸ | CTRC | Q99895 | 2/20 | 0.52 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.49 |
| ▸ | SENP2 | Q9HC62 | 2/20 | 0.45 |
| ▸ | SENP1 | Q9P0U3 | 2/20 | 0.45 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.45 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP3 | Q9H4L4 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16749787 | 0.88 | MPL (0.65) | MPLCTRCGLO1SENP2SENP1 | |
| SCHEMBL10049018 | 0.83 | MPL (0.77) | MPLCTRCGLO1SENP7CYP1A2 | |
| SCHEMBL16749785 | 0.81 | CYP2C19 (0.64) | MPLCTRCGLO1SENP2SENP1 | |
| SCHEMBL12206631 | 0.78 | MPL (0.81) | MPLCTRCCYP1A2CYP2C9TSHR | |
| SCHEMBL17550007 | 0.75 | MAPT (0.58) | MPLCTRCGLO1SENP2SENP1 | |
| SCHEMBL27016948 | 0.73 | CYP1A2 (0.82) | MPLCTRCCYP1A2CYP2C9TSHR | |
| SCHEMBL10724086 | 0.73 | GLO1 (0.82) | MPLCTRCGLO1SENP2SENP1 | |
| SCHEMBL10724094 | 0.73 | GLO1 (0.82) | MPLCTRCGLO1SENP2SENP1 | |
| SCHEMBL10723387 | 0.72 | GLO1 (0.80) | MPLCTRCGLO1SENP2SENP1 | |
| SCHEMBL13420016 | 0.72 | MPL (0.79) | MPLCTRCGLO1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2855597-B1 | REACTIVE DYES, THEIR PREPARATION AND THEIR USE | HUNTSMAN ADVANCED MAT (SWITZERLAND) GMBH (CH) | 2017-06-07 | — | — | EP | disclosed |