Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 13/20 | 0.54 |
| ▸ | CA2 | P00918 | 13/20 | 0.54 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18975015 | 1.00 | CA1 (0.54) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL18955991 | 0.89 | CA1 (0.45) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL18955513 | 0.88 | CA1 (0.48) | CA1CA2CA12CA9CA4 | |
| SCHEMBL18955344 | 0.88 | CA1 (0.48) | CA1CA2CA12CA9P2RX4 | |
| SCHEMBL18955569 | 0.86 | CA1 (0.45) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL18955346 | 0.85 | CA1 (0.44) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL18955836 | 0.85 | CA1 (0.49) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL18955687 | 0.84 | P2RX4 (0.40) | CA1CA2ALDH1A1MAPTP2RX4 | |
| SCHEMBL18955402 | 0.84 | P2RX4 (0.40) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL18955528 | 0.82 | ALDH1A1 (0.43) | CA1CA2ALDH1A1MAPTP2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017099695-A1 | N-[(AMINOSULFONYL)PHENYL]-2-(1,2-DIHYDRO-2-OXO-3H-INDOL-3-YLIDENE)-HYDRAZINECARBOTHIOAMIDE DERIVATIVES FOR TREATING CANCER AND IMMUNOLOGICAL DISORDERS | ISTANBUL UNIVERSITESI REKTORLUGU (TR) | 2017-06-15 | — | — | WO | disclosed |
| WO-2017099695-A1 | N-[(AMINOSULFONYL)PHENYL]-2-(1,2-DIHYDRO-2-OXO-3H-INDOL-3-YLIDENE)-HYDRAZINECARBOTHIOAMIDE DERIVATIVES FOR TREATING CANCER AND IMMUNOLOGICAL DISORDERS | ISTANBUL UNIVERSITESI REKTORLUGU (TR) | 2017-06-15 | — | — | WO | disclosed |