⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL440213 | 0.74 | — | — | |
| SCHEMBL558166 | 0.70 | — | — | |
| SCHEMBL791761 | 0.70 | — | — | |
| SCHEMBL18938749 | 0.70 | — | — | |
| SCHEMBL1149574 | 0.67 | TRPV4 (0.31) | — | |
| SCHEMBL18938653 | 0.65 | — | — | |
| SCHEMBL18938793 | 0.65 | — | — | |
| SCHEMBL29828757 | 0.62 | — | — | |
| SCHEMBL2043832 | 0.62 | — | — | |
| SCHEMBL12902021 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9957248-B2 | Substituted 5-hydroxy-2-heteroaryl-3-phenylpentanonitrile derivatives, processes for their preparation and their use as herbicides and/or plant growth regulators | BAYER CROPSCIENCE AKTIENGESELLSHAFT (DE) | 2018-05-01 | — | — | US | disclosed |
| US-20170166549-A1 | Substituted 5-hydroxy-2-heteroaryl-3-phenylpentanonitrile derivatives, processes for their preparation and their use as herbicides and/or plant growth regulators | BAYER CROPSCIENCE AKTIENGESELLSHAFT (DE) | 2017-06-15 | — | — | US | disclosed |