Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 10/20 | 0.43 |
| ▸ | CA2 | P00918 | 9/20 | 0.43 |
| ▸ | CA12 | O43570 | 7/20 | 0.43 |
| ▸ | CA9 | Q16790 | 6/20 | 0.43 |
| ▸ | STK17B | O94768 | 1/20 | 0.39 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19978199 | 0.80 | CA1 (0.35) | TDP1MEN1KMT2AGAACA1 | |
| SCHEMBL18940165 | 0.79 | TDP1 (0.47) | TDP1MEN1KMT2AGAAMAOA | |
| SCHEMBL569251 | 0.79 | TDP1 (0.74) | TDP1MEN1KMT2AGAAMAOA | |
| SCHEMBL22169354 | 0.78 | TDP1 (0.35) | TDP1MEN1KMT2AGAAMAOA | |
| SCHEMBL18681191 | 0.77 | IDO1 (0.43) | TDP1MEN1KMT2AGAAMAOA | |
| SCHEMBL15575825 | 0.76 | TDP1 (0.57) | TDP1MEN1KMT2AGAAMAOA | |
| SCHEMBL17934110 | 0.76 | TDP1 (0.61) | TDP1MEN1KMT2AGAAMAOA | |
| SCHEMBL18100118 | 0.75 | TDP1 (0.56) | TDP1MEN1KMT2AGAAMAOA | |
| SCHEMBL18938501 | 0.75 | TDP1 (0.49) | TDP1MEN1KMT2AGAAMAOA | |
| SCHEMBL3020258 | 0.75 | TDP1 (0.81) | TDP1MEN1KMT2AGAAMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017096045-A1 | MULTIVALENT RAS BINDING COMPOUNDS | KYRAS THERAPEUTICS, INC. (US) | 2017-06-08 | — | — | WO | disclosed |