Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.81 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.69 |
| ▸ | MAOA | P21397 | 1/20 | 0.68 |
| ▸ | MAOB | P27338 | 1/20 | 0.68 |
| ▸ | CA1 | P00915 | 7/20 | 0.64 |
| ▸ | CA2 | P00918 | 7/20 | 0.64 |
| ▸ | CA12 | O43570 | 6/20 | 0.64 |
| ▸ | CA9 | Q16790 | 6/20 | 0.64 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | STK17B | O94768 | 1/20 | 0.48 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL140853 | 0.98 | TDP1 (0.85) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL343629 | 0.98 | TDP1 (0.85) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL343419 | 0.98 | TDP1 (0.85) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL136815 | 0.98 | TDP1 (0.85) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL137629 | 0.98 | TDP1 (0.85) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL3025184 | 0.98 | TDP1 (0.85) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL134329 | 0.98 | TDP1 (0.85) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL5162656 | 0.98 | TDP1 (0.85) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL569251 | 0.95 | TDP1 (0.74) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL14242963 | 0.94 | TDP1 (0.72) | TDP1MEN1GAAKMT2AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240345094-A1 | DOUBLE FRAGMENTATION ISOBARIC TAGGING | SAINT LOUIS UNIVERSITY (US) | 2024-10-17 | — | — | US | disclosed |
| CN-114599662-A | Neomycin-based compounds and pharmaceutical uses thereof | 蔚蓝海岸大学 | 2022-06-07 | — | — | CN | disclosed |
| US-9872918-B2 | Hydroxyl-polymer-drug-protein conjugates | MERSANA THERAPEUTICS, INC. (US) | 2018-01-23 | — | — | US | disclosed |
| US-9770519-B2 | Protein-polymer-drug conjugates | MERSANA THERAPEUTICS, INC. (US) | 2017-09-26 | — | — | US | disclosed |
| US-20170119896-A1 | TERMINALLY MODIFIED POLYMERS AND CONJUGATES THEREOF | MERSANA THERAPEUTICS, INC. | 2017-05-04 | — | — | US | disclosed |
| US-8715635-B2 | Frictionless molecular rotary motors | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2014-05-06 | — | — | US | disclosed |
| US-8658346-B2 | Pattern forming process, chemically amplified positive resist composition, and resist-modifying composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2014-02-25 | — | — | US | disclosed |
| US-8426105-B2 | Resist-modifying composition and pattern forming process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2013-04-23 | — | — | US | disclosed |
| US-8426105-B2 | Resist-modifying composition and pattern forming process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2013-04-23 | — | — | US | disclosed |
| US-8329384-B2 | Resist-modifying composition and pattern forming process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2012-12-11 | — | — | US | disclosed |
| US-7531676-B2 | Lipids | CELLTECH R & D LIMITED (GB) | 2009-05-12 | — | — | US | disclosed |
| WO-2008096360-A2 | FRICTIONLESS MOLECULAR ROTARY MOTORS | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) | 2008-08-14 | — | — | WO | disclosed |
| WO-2008096360-A2 | FRICTIONLESS MOLECULAR ROTARY MOTORS | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) | 2008-08-14 | — | — | WO | disclosed |
| US-20060148761-A1 | Lipids | CELLTECH R & D LIMITED | 2006-07-06 | — | — | US | disclosed |
| US-20040024220-A1 | Lipids | CELLTECH R & D LIMITED | 2004-02-05 | — | — | US | disclosed |
| US-6583301-B1 | Bipolar; form complexes with polyanions; delivering bioactive substances such as nucleic acids to cells in vitro and in vivo | CELLTECH R & D LIMITED (GB) | 2003-06-24 | — | — | US | disclosed |
| EP-1204428-A2 | TARGETED LIPID PARTICLES | Celltech R&D Limited (GB) | 2002-05-15 | — | — | EP | disclosed |
| WO-2001012154-A2 | TARGETED LIPID PARTICLES | CELLTECH R&D LIMITED (GB) | 2001-02-22 | — | — | WO | disclosed |
| EP-1070047-A2 | LIPIDS | Celltech Chiroscience Limited (GB) | 2001-01-24 | — | — | EP | disclosed |
| WO-1999052858-A2 | LIPIDS | CELLTECH THERAPEUTICS LIMITED (GB) | 1999-10-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040024220-A1 | Lipids | PHOSPHO1, FABP7, MBOAT7 | TDP1 1253/4885MEN1 1304/4885GAA 858/4885 |
| US-20060148761-A1 | Lipids | PHOSPHO1, FABP7, MBOAT7 | TDP1 1253/4885MEN1 1304/4885GAA 858/4885 |
| US-20170119896-A1 | TERMINALLY MODIFIED POLYMERS AND CONJUGATES THEREOF | MALT1, ALG1, PRMT3 | TDP1 1452/4885MEN1 1055/4885GAA 1601/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.