Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.45 |
| ▸ | APOBEC3A | P31941 | 4/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 7/20 | 0.37 |
| ▸ | NPC1 | O15118 | 7/20 | 0.37 |
| ▸ | RAB9A | P51151 | 7/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL372853 | 0.98 | HDAC8 (0.47) | HDAC8APOBEC3AAPOBEC3GSMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL30980120 | 0.96 | HDAC8 (0.45) | HDAC8APOBEC3AAPOBEC3GSMN1; SMN2KDM4E | |
| SCHEMBL1835131 | 0.92 | HDAC8 (0.42) | HDAC8APOBEC3AAPOBEC3GSMN1; SMN2KDM4E | |
| SCHEMBL30645316 | 0.91 | NPC1 (0.43) | HDAC8APOBEC3AAPOBEC3GSMN1; SMN2KDM4E | |
| SCHEMBL1831748 | 0.91 | NPC1 (0.43) | HDAC8APOBEC3AAPOBEC3GSMN1; SMN2KDM4E | |
| SCHEMBL29048074 | 0.91 | NPC1 (0.43) | HDAC8APOBEC3AAPOBEC3GSMN1; SMN2KDM4E | |
| SCHEMBL6296126 | 0.91 | NPC1 (0.43) | HDAC8APOBEC3AAPOBEC3GSMN1; SMN2KDM4E | |
| SCHEMBL1835103 | 0.91 | NPC1 (0.43) | HDAC8APOBEC3AAPOBEC3GSMN1; SMN2KDM4E | |
| SCHEMBL20787057 | 0.91 | NPC1 (0.43) | HDAC8APOBEC3AAPOBEC3GSMN1; SMN2KDM4E | |
| SCHEMBL1832602 | 0.91 | NPC1 (0.43) | HDAC8APOBEC3AAPOBEC3GSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1698606-B1 | FLUORINATING AGENT AND METHOD FOR PRODUCING FLUORINE-CONTAINING COMPOUND USING SAME | SUMITOMO CHEMICAL CO (JP) | 2013-02-20 | — | — | EP | disclosed |
| US-7939697-B2 | Fluorinating agent and method for producing fluorine-containing compound using the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-05-10 | — | — | US | disclosed |
| US-20090287025-A1 | Fluorinating agent and method for producing fluorine-containing compound using the same | SUMITOMO CHEMICAL COMPANY, LIMITED | 2009-11-19 | — | — | US | disclosed |
| US-7569703-B2 | Fluorinating agent and method for producing fluorine-containing compound using the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-08-04 | — | — | US | disclosed |
| US-20070135634-A1 | Fluorinating agent and method for producing fluorine-containing compound using the same | SUMITOMO CHEMICAL COMPANY, LIMITED | 2007-06-14 | — | — | US | disclosed |
| EP-1698606-A1 | FLUORINATING AGENT AND METHOD FOR PRODUCING FLUORINE-CONTAINING COMPOUND USING SAME | Sumitomo Chemical Company, Limited (JP) | 2006-09-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135634-A1 | Fluorinating agent and method for producing fluorine-containing compound using the same | AFF1, AFF2, AFF4 | HDAC8 3030/4885APOBEC3A 3356/4885APOBEC3G 2986/4885 |
| US-20090287025-A1 | Fluorinating agent and method for producing fluorine-containing compound using the same | AFF1, AFF2, AFF4 | HDAC8 3030/4885APOBEC3A 3356/4885APOBEC3G 2986/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.