Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX4 | Q9NPH5 | 18/20 | 0.50 |
| ▸ | CYBB | P04839 | 10/20 | 0.50 |
| ▸ | NOX1 | Q9Y5S8 | 9/20 | 0.44 |
| ▸ | NOX5 | Q96PH1 | 8/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14931671 | 0.91 | NOX4 (0.51) | NOX4CYBBNOX1NOX5CYP3A4 | |
| SCHEMBL29523089 | 0.91 | NOX4 (0.51) | NOX4CYBBNOX1NOX5CYP3A4 | |
| SCHEMBL29523126 | 0.91 | NOX4 (0.51) | NOX4CYBBNOX1NOX5CYP3A4 | |
| SCHEMBL14931684 | 0.91 | NOX4 (0.51) | NOX4CYBBNOX1NOX5CYP3A4 | |
| SCHEMBL14931723 | 0.88 | NOX4 (0.51) | NOX4CYBBNOX1NOX5CYP3A4 | |
| SCHEMBL29523385 | 0.88 | NOX4 (0.51) | NOX4CYBBNOX1NOX5CYP3A4 | |
| SCHEMBL14931691 | 0.87 | NOX4 (0.51) | NOX4CYBBNOX1NOX5CYP3A4 | |
| SCHEMBL29523256 | 0.87 | NOX4 (0.51) | NOX4CYBBNOX1NOX5CYP3A4 | |
| SCHEMBL14931562 | 0.82 | NOX4 (0.72) | NOX4CYBBNOX1NOX5CYP3A4 | |
| SCHEMBL29523172 | 0.82 | NOX4 (0.72) | NOX4CYBBNOX1NOX5CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2776027-B1 | NADPH OXIDASE 4 INHIBITORS AND USE THEREOF | GENKYOTEX SUISSE SA (CH) | 2017-06-07 | — | — | EP | disclosed |